Population pharmacokinetics of antibacterial agents in the older population: a literature review
HX Liu, BH Tang, J van den Anker, GX Hao… - Expert review of …, 2024 - Taylor & Francis
Introduction Older individuals face an elevated risk of developing bacterial infections. The
optimal use of antibacterial agents in this population is challenging because of age-related …
optimal use of antibacterial agents in this population is challenging because of age-related …
Pharmacokinetics of antibacterial agents in the elderly: the body of evidence
OI Butranova, EA Ushkalova, SK Zyryanov… - Biomedicines, 2023 - mdpi.com
Infections are important factors contributing to the morbidity and mortality among elderly
patients. High rates of consumption of antimicrobial agents by the elderly may result in …
patients. High rates of consumption of antimicrobial agents by the elderly may result in …
Antimicrobial pharmacokinetics and pharmacodynamics in older adults
JM Benson - Infectious Disease Clinics, 2017 - id.theclinics.com
Although it is now the eighth decade of the antibiotic era, with the commensurate wealth of
data, there are still areas that require greater exploration. The pharmacokinetic (PK), and …
data, there are still areas that require greater exploration. The pharmacokinetic (PK), and …
Pharmacokinetics and drug metabolism of antibiotics in the elderly
F Pea - Expert Opinion on Drug Metabolism & Toxicology, 2018 - Taylor & Francis
Introduction: The number of elderly people is increasing worldwide. The elderly may be at
increased risk of bacterial infections compared with younger adults. Dosing adaptation of …
increased risk of bacterial infections compared with younger adults. Dosing adaptation of …
Adjust antimicrobial agent regimens in older patients to correct for changes in pharmacokinetics and to avoid adverse events
S Fung - Drugs & Therapy Perspectives, 2024 - Springer
Treating infections with antimicrobial agents in older patients can be challenging.
Physiological changes associated with aging can alter the pharmacokinetics of antimicrobial …
Physiological changes associated with aging can alter the pharmacokinetics of antimicrobial …
Review of antimicrobial use and considerations in the elderly population
A Giarratano, SEL Green… - Clinical interventions in …, 2018 - Taylor & Francis
Pharmacologic management of infections in elderly patients presents multiple challenges to
health care professionals due to variable pharmacokinetics, pharmacodynamics, and …
health care professionals due to variable pharmacokinetics, pharmacodynamics, and …
Principles of antimicrobial use in older adults
AR Herring, JC Williamson - Clinics in geriatric medicine, 2007 - Elsevier
The fundamental principles of treating infectious diseases apply to elderly patients, but
certain aspects of therapy such as the selection of empiric regimens and risk stratification for …
certain aspects of therapy such as the selection of empiric regimens and risk stratification for …
Use of pharmacodynamic principles to optimise dosage regimens for antibacterial agents in the elderly
AM Noreddin, V Haynes - Drugs & aging, 2007 - Springer
Throughout most of the world we are witnessing an ever increasing number of aged people
as a percentage of the general population. In the coming years, the unique spectrum of …
as a percentage of the general population. In the coming years, the unique spectrum of …
Safety and tolerability of antimicrobial agents in the older patient
L Soraci, A Cherubini, L Paoletti, G Filippelli, F Luciani… - Drugs & Aging, 2023 - Springer
Older patients are at high risk of infections, which often present atypically and are associated
with high morbidity and mortality. Antimicrobial treatment in older individuals with infectious …
with high morbidity and mortality. Antimicrobial treatment in older individuals with infectious …
Unique aspects of antimicrobial use in older adults
CM Faulkner, HL Cox… - Clinical infectious …, 2005 - academic.oup.com
Elderly persons consume a significant proportion of health care resources. Antimicrobials
are just one class among many pharmaceuticals that are prescribed more frequently to …
are just one class among many pharmaceuticals that are prescribed more frequently to …
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