A rise in blood flow velocity variations (ie pulsatility) in the brain, caused by the stiffening of
upstream arteries, is associated with cognitive impairment and neurodegenerative diseases …

An increased pulse pressure, due to arteries stiffening with age and cardiovascular disease,
may lead to downstream brain damage in microvessels and cognitive decline. Brain-wide …

Cardiovascular diseases are associated with cognitive impairment. Aging arteries increased
stiffness leads to an increased pulsatility in downstream vessels and brain structural …

Abstract Changes in cerebral blood flow are associated with stroke, aneurysms, vascular
cognitive impairment, neurodegenerative diseases and other pathologies. Brain …

The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed
using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization …

Abstract Objective Dynamic Ultrasound Localization Microscopy (DULM) has first been
developed for non-invasive Pulsatility measurements in the rodent brain. DULM relies on the …

Hemodynamic changes occur in stroke and neurodegenerative diseases. Developing
imaging techniques allowing the in vivo visualization and quantification of cerebral blood …

The advent of neuroimaging has increased our understanding of brain function. While most
brain-wide functional imaging modalities exploit neurovascular coupling to map brain …

Technologies to visualize whole organs across scales in vivo are essential for our
understanding of biology in health and disease. To date, only post-mortem techniques …

Ultrasound Localization Microscopy has demonstrated the ability to overcome the
penetration/resolution conundrum in ultrasound imaging thanks to high frame rate imaging …