[HTML][HTML] Roles of strong scalar couplings in maximizing glutamate, glutamine and glutathione pseudo singlets at 7 tesla

L An, JW Evans, C Burton, JS Tomar… - Frontiers in …, 2022 - frontiersin.org
For the H4 protons of glutamate (Glu), glutamine (Gln), and the glutamyl moiety of
glutathione (GSH), the effect of the internal strong scalar coupling between the two …

Improved resolution of glutamate, glutamine and γ‐aminobutyric acid with optimized point‐resolved spectroscopy sequence timings for their simultaneous …

BJ Dobberthien, AG Tessier, A Yahya - NMR in Biomedicine, 2018 - Wiley Online Library
Glutamine (Gln), glutamate (Glu) and γ‐aminobutyric acid (GABA) are relevant brain
metabolites that can be measured with magnetic resonance spectroscopy (MRS). This work …

Exploiting the chemical shift displacement effect in the detection of glutamate and glutamine (Glx) with PRESS

A Yahya, B Mädler, BG Fallone - Journal of magnetic resonance, 2008 - Elsevier
A PRESS (Point RESolved Spectroscopy) sequence for the improved detection of the C2
protons of Glx (glutamate and glutamine) at≈ 3.75 ppm is presented in this work. It is shown …

Improvement of resolution for brain coupled metabolites by optimized 1H MRS at 7 T

C Choi, IE Dimitrov, D Douglas, A Patel… - NMR in …, 2010 - Wiley Online Library
Resolution enhancement for glutamate (Glu), glutamine (Gln) and glutathione (GSH) in the
human brain by TE‐optimized point‐resolved spectroscopy (PRESS) at 7 T is reported. Sub …

Detection of glutamate, glutamine, and glutathione by radiofrequency suppression and echo time optimization at 7 tesla

L An, S Li, JB Murdoch, MF Araneta… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To achieve detection of glutamate (Glu), glutamine (Gln), and glutathione (GSH) by
minimizing the N‐acetyl‐aspartate (NAA) multiplet signals at 2.49 ppm using a echo time …

Simultaneous detection of resolved glutamate, glutamine, and γ-aminobutyric acid at 4 T

J Hu, S Yang, Y Xuan, Q Jiang, Y Yang… - Journal of magnetic …, 2007 - Elsevier
A new approach is introduced to simultaneously detect resolved glutamate (Glu), glutamine
(Gln), and γ-aminobutyric acid (GABA) using a standard STEAM localization pulse sequence …

Optimized multi-voxel TE-averaged PRESS for glutamate detection in the human brain at 3T

GH Hatay, E Ozturk-Isik - Journal of Magnetic Resonance, 2023 - Elsevier
Purpose To optimize possible combinations of echo times (TE) for multi-voxel TE-averaged
Point RESolved Spectroscopy (PRESS) while reducing the total number of TEs required to …

[PDF][PDF] Detection of glutamate in the human brain at 3 Tesla using optimized CT-PRESS

D Mayer, DM Spielman - Proceedings of the 10th Scientific Meeting …, 2002 - cds.ismrm.org
Abstract A CT-PRESS sequence was implemented on a 3 T MR scanner and optimized for
the detection of the C4 resonance of glutamate. The sequence was tested on phantoms …

Distinguishing glutamate and glutamine in in vivo 1H MRS based on nuclear spin singlet order filtering

JX Xin, DX Wei, Y Ren, JL Wang… - Magnetic …, 2023 - Wiley Online Library
Purpose The signals of glutamate (Glu) and glutamine (Gln) are often significantly
overlapped in routine 1H‐MR spectra of human brain in vivo. Selectively probing the signals …

Improved detection limits of J‐coupled neurometabolites in the human brain at 7 T with a J‐refocused sLASER sequence

C Najac, VO Boer, HE Kan, AG Webb… - NMR in …, 2022 - Wiley Online Library
In a standard spin echo, the time evolution due to homonuclear couplings is not reversed,
leading to echo time (TE)‐dependent modulation of the signal amplitude and signal loss in …