Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention
S Kaufhold, B Bonavida - Journal of Experimental & Clinical Cancer …, 2014 - Springer
Snail1 is the founding member of the Snail superfamily of zinc-finger transcription factors,
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …
SNAIL1: linking tumor metastasis to immune evasion
X Tang, X Sui, L Weng, Y Liu - Frontiers in immunology, 2021 - frontiersin.org
The transcription factor Snail1, a key inducer of epithelial-mesenchymal transition (EMT),
plays a critical role in tumor metastasis. Its stability is strictly controlled by multiple …
plays a critical role in tumor metastasis. Its stability is strictly controlled by multiple …
Snail1-dependent activation of cancer-associated fibroblast controls epithelial tumor cell invasion and metastasis
L Alba-Castellón, R Olivera-Salguero, A Mestre-Farrera… - Cancer research, 2016 - AACR
Snail1 transcriptional factor is essential for triggering epithelial-to-mesenchymal transition
(EMT) and inducing tumor cell invasion. We report here an EMT-independent action of …
(EMT) and inducing tumor cell invasion. We report here an EMT-independent action of …
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines
Abstract Snai1 (Snail) and Snai2 (Slug), the two main members of Snail family factors, are
important mediators of epithelial-mesenchymal transitions and involved in tumor …
important mediators of epithelial-mesenchymal transitions and involved in tumor …
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
Snail1 is a zinc finger transcriptional repressor whose pathological expression has been
linked to cancer cell epithelial–mesenchymal transition (EMT) programs and the induction of …
linked to cancer cell epithelial–mesenchymal transition (EMT) programs and the induction of …
SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells
The transcription factor, SNAI1 (Snail), has recently been proposed as an important mediator
of tumor invasion because of its role in E-cadherin down-regulation and induction of …
of tumor invasion because of its role in E-cadherin down-regulation and induction of …
Transient SNAIL1 expression is necessary for metastatic competence in breast cancer
HD Tran, K Luitel, M Kim, K Zhang, GD Longmore… - Cancer research, 2014 - AACR
SNAIL1 has been suggested to regulate breast cancer metastasis based on analyses of
human breast tumor transcriptomes and experiments using cancer cell lines and xenografts …
human breast tumor transcriptomes and experiments using cancer cell lines and xenografts …
Molecular regulation of Snai2 in development and disease
W Zhou, KM Gross, C Kuperwasser - Journal of cell science, 2019 - journals.biologists.com
The transcription factor Snai2, encoded by the SNAI2 gene, is an evolutionarily conserved
C2H2 zinc finger protein that orchestrates biological processes critical to tissue development …
C2H2 zinc finger protein that orchestrates biological processes critical to tissue development …
Effect of modulation of epithelial‑mesenchymal transition regulators Snail1 and Snail2 on cancer cell radiosensitivity by targeting of the cell cycle, cell apoptosis and …
G Assani, Y Zhou - Oncology letters, 2019 - spandidos-publications.com
Cancer is one of the leading causes of cancer‑associated mortality worldwide. Several
strategies of treatment, including radiotherapy, have been developed and used to treat this …
strategies of treatment, including radiotherapy, have been developed and used to treat this …
Snail: more than EMT
Y Wu, BP Zhou - Cell adhesion & migration, 2010 - Taylor & Francis
Snail has moved into the fast lane of development and cancer biology with the epithelial-
mesenchymal transition (EMT) emerging as one of the hottest topics in medical science …
mesenchymal transition (EMT) emerging as one of the hottest topics in medical science …