Immunogenic cell death inducers for cancer therapy: an emerging focus on natural products

LL Zhang, DJ Zhang, JX Shi, MY Huang, JM Yu… - Phytomedicine, 2024 - Elsevier
Background Immunogenic cell death (ICD) is a specific form of regulated cell death induced
by a variety of stressors. During ICD, the dying cancer cells release damage-associated …

[HTML][HTML] Plant-derived natural compounds: A new frontier in inducing immunogenic cell death for cancer treatment

L Yang, T Han, R Liu, S Shi, S Luan, S Meng - Biomedicine & …, 2024 - Elsevier
Immunogenic cell death (ICD) can activate adaptive immune response in the host with
normal immune system. Some synthetic chemotherapeutic drugs and natural compounds …

[HTML][HTML] Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds

M Amiri, O Molavi, S Sabetkam, S Jafari… - Cancer Cell …, 2023 - Springer
A growing body of evidence indicates that the anticancer effect of the immune system can be
activated by the immunogenic modulation of dying cancer cells. Cancer cell death, as a …

Immunogenic cell death in cancer therapy: Present and emerging inducers

J Zhou, G Wang, Y Chen, H Wang… - Journal of cellular and …, 2019 - Wiley Online Library
In the tumour microenvironment (TME), immunogenic cell death (ICD) plays a major role in
stimulating the dysfunctional antitumour immune system. Chronic exposure of damage …

Natural modulators of the hallmarks of immunogenic cell death

F Radogna, M Dicato, M Diederich - Biochemical Pharmacology, 2019 - Elsevier
Natural compounds act as immunoadjuvants as their therapeutic effects trigger cancer stress
response and release of damage-associated molecular patterns (DAMPs). These reactions …

[HTML][HTML] Research progress in inducing immunogenic cell death of tumor cells

D Xie, Q Wang, G Wu - Frontiers in immunology, 2022 - frontiersin.org
Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …

Reinforcing the immunogenic cell death to enhance cancer immunotherapy efficacy

S Yu, H Xiao, L Ma, J Zhang, J Zhang - Biochimica et Biophysica Acta (BBA …, 2023 - Elsevier
Immunogenic cell death (ICD) has been a revolutionary modality in cancer treatment since it
kills primary tumors and prevents recurrent malignancy simultaneously. ICD represents a …

Immunogenic cell death inducers for enhanced cancer immunotherapy

Y Li, X Liu, X Zhang, W Pan, N Li, B Tang - Chemical Communications, 2021 - pubs.rsc.org
Inducing the immunogenic cell death (ICD) of cancer cells is an important method to improve
the immunogenicity of tumor cells for enhanced cancer immunotherapy. Therefore, we …

Clinical application of immunogenic cell death inducers in cancer immunotherapy: turning cold tumors hot

Y Han, X Tian, J Zhai, Z Zhang - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Immunotherapy has emerged as a promising cancer treatment option in recent years. In
immune “hot” tumors, characterized by abundant immune cell infiltration, immunotherapy …

[HTML][HTML] Chemotherapeutic and targeted drugs-induced immunogenic cell death in cancer models and antitumor therapy: An update review

J Zhai, X Gu, Y Liu, Y Hu, Y Jiang… - Frontiers in …, 2023 - frontiersin.org
As traditional strategies for cancer treatment, some chemotherapy agents, such as
doxorubicin, oxaliplatin, cyclophosphamide, bortezomib, and paclitaxel exert their anti-tumor …