Parkinson's disease and parkinsonism: neuropathology

DW Dickson - Cold Spring Harbor perspectives …, 2012 - perspectivesinmedicine.cshlp.org
Parkinsonism, the clinical term for a disorder with prominent bradykinesia and variable
associated extrapyramidal signs and symptoms, is accompanied by degeneration of the …

Neuropathology of Parkinson disease

DW Dickson - Parkinsonism & related disorders, 2018 - Elsevier
Introduction Parkinson's disease (PD) is characterized by bradykinesia, rigidity, postural
instability and tremor. Several pathologic processes can produce this syndrome, but …

Neuropathology of non-motor features of Parkinson disease

DW Dickson, H Fujishiro, C Orr, A DelleDonne… - Parkinsonism & related …, 2009 - Elsevier
Non-motor manifestations of Parkinson disease (PD) are common and some may actually
antedate motor dysfunction. Extrapyramidal signs in PD are tightly linked to striatonigral …

[HTML][HTML] Parkinson's: a syndrome rather than a disease?

N Titova, C Padmakumar, SJG Lewis… - Journal of Neural …, 2017 - Springer
Emerging concepts suggest that a multitude of pathology ranging from misfolding of alpha-
synuclein to neuroinflammation, mitochondrial dysfunction, and neurotransmitter driven …

Parkinson's disease: etiology, neuropathology, and pathogenesis

A Kouli, KM Torsney, WL Kuan - Exon Publications, 2018 - exonpublications.com
Parkinson's disease (PD) is a common neurodegenerative disorder. While a number of
nonmotor manifestations arise, the typical clinical features involve a movement disorder …

Parkinson's disease

KA Jellinger - … : the molecular pathology of dementia and …, 2011 - Wiley Online Library
Parkinson's disease is the most frequent neurodegenerative movement disorder,
characterized by degeneration of the dopaminergic nigrostriatal and other neuronal …

Recent developments in the pathology of Parkinson's disease

KA Jellinger - Ageing and Dementia Current and Future Concepts, 2002 - Springer
Parkinson's disease (PD) is morphologically characterized by progressive loss of neurons in
the substantia nigra pars compacta (SNpc) and other subcortical nuclei associated with …

Parkinson's disease: premotor clinico-pathological correlations

EC Wolters, H Braak - Parkinson's Disease and Related Disorders, 2006 - Springer
Parkinsonism is a clinical syndrome characterized by bradykinesia, hypo-/akinesia,
muscular rigidity, and resting tremor, mainly caused by Parkinson's disease (PD) …

Parkinson disease

R Balestrino, AHV Schapira - European journal of neurology, 2020 - Wiley Online Library
Parkinson disease (PD) is the most common neurodegenerative movement disorder. In
Europe, prevalence and incidence rates for PD are estimated at approximately 108–257/100 …

Variability in the clinical expression of Parkinson's disease

EC Wolters - Journal of the neurological sciences, 2008 - Elsevier
Parkinsonism is a clinical syndrome characterized by bradykinesia, hypo-/akinesia,
muscular rigidity, and resting tremor, mainly caused by Parkinson's disease (PD). Symptoms …