3-Allyl-2-(allylthio)-5, 5-diphenyl-3, 5-dihydro-4H-imidazol-4-one: Synthesis, spectroscopic characterization, crystal structure, computational investigations …

AEMA Allah, E Temel, W Guerrab, I Nchioua… - Journal of Molecular …, 2024 - Elsevier
In this investigation, we successfully synthesized a novel thiohydantoin derivative, 3-allyl-2-
(allylthio)-5, 5-diphenyl-3, 5-dihydro-4H-imidazol-4-one (AM 1). The compound underwent …

Synthesis, characterization, and antimicrobial analysis of 5-phenyl-4-((2-(piperazin-1-yl) ethyl) thio)-1, 2, 3-oxadiazole analogs through in vitro and in silico approach

VL Ranganatha, R Ramu, V Rashmi, RM Martiz… - Journal of Molecular …, 2022 - Elsevier
Oxadiazoles and 1, 2, 3-oxadiazoles are well known heterocyclic compounds, which acts
both as biomimetic and reactive pharmacophores. Many of them are key compounds with …

Synthesis, crystal structure, Hirshfeld surface analysis, computational investigations and molecular docking studies of (Z)-3-N-(methyl)-2-N'-(4-methoxyphenylimino) …

SA Kaas, FT Baara, Y Megrouss, S Yahiaoui… - Journal of Molecular …, 2024 - Elsevier
Thiazolidinones, widely utilized as a framework for synthesizing diverse molecules,
demonstrate pharmacological activity and contribute to the creation of compounds with …

[HTML][HTML] Design, Synthesis and Antibacterial Activity Evaluation of 4, 5-Diphenyl-1H-Imidazoles Derivatives

C Bamoro, F Bamba, KTD Steve-Evanes… - Open Journal of …, 2021 - scirp.org
Due to the continuous emergence and rapid spread of drug-resistant strains of bacteria,
there is an urgent need for the development of novel antimicrobials. Along this line, the …

Synthesis, crystal structure, spectroscopic, thermal properties and DFT calculation of a novel ethyl 2-(2-(thiazol-4-yl)-1H-benzimidazol-1-yl) acetate

L El Foujji, K El Bourakadi, MEM Mekhzoum… - Journal of Molecular …, 2020 - Elsevier
In the present study, we report the synthesis, molecular structure, molecular docking, the
spectral characterization such as NMR, FT-IR and FT-Raman analysis and electronic …

2, 6-disubstituted imidazothiadiazole 5-carbaldehyde: Synthesis, crystal structure elucidation and in-silico studies

KS Sagar, S Shamanth, K Kumara, NK Lokanath… - Chemical Data …, 2022 - Elsevier
The synthesis of novel imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives through the reaction of
3, 4 dimethoxy phenylacetic acid with various 2 bromo acetophenones is been presented …

Spectroscopic characterization, X-ray structure and DFT studies on 4-[3-(2, 5-dimethylphenyl)-3-methylcyclobutyl]-N-methylthiazol-2-amine

H Saraçoğlu, Ö Ekici - Journal of Structural Chemistry, 2015 - Springer
Abstract The titled molecule 4-[3-(2, 5-dimethylphenyl)-3-methylcyclobutyl]-N-methylthiazol-
2-amine (C 17 H 22 N 2 S) is synthesized and characterized by 1 H NMR, 13 C NMR, IR …

Synthesis, characterization, docking study and antimicrobial activity of 2-(4-benzoylphenoxy)-1-[2-(1-methyl-1H-indol-3-yl)methyl)-1H-benzo[d]imidazol-1-yl] …

T Prashanth, VL Ranganatha, R Ramu… - Journal of the Iranian …, 2021 - Springer
The occurrence of drug-resistant bacterial infections impulses the development of new
antibacterial agents that own a mechanism of action different from traditional antibiotics …

Design and synthesis of new 4-methylthiazole derivatives: In vitro and in silico studies of antimicrobial activity

AE Evren, S Dawbaa, N Demokrat, ŞA Yavuz… - Journal of Molecular …, 2021 - Elsevier
The development of resistance against antimicrobial drugs has become a world-wide issue.
It is predicted that some or perhaps all the antimicrobial drugs used in clinics will be out of …

New indazole–1, 2, 3–triazoles as potent antimicrobial agents: Design, synthesis, molecular modeling and in silico ADME profiles

SK Gandham, AA Kudale, TR Allaka, K Chepuri… - Journal of Molecular …, 2024 - Elsevier
Our current work is aimed at synthesizing novel derivatives of 1, 2, 3–triazolyl–indazoles,
applying docking techniques and biological evaluation in order to find active promising …