The aryl hydrocarbon receptor (Ah receptor or AHR) is a ligand-activated transcription factor
involved in the regulation of several genes, including those for xenobiotic-metabolizing …

The aryl hydrocarbon receptor (AhR) is a highly evolutionary conserved, ligand-activated
transcription factor that is best known to mediate the toxicities of dioxins and dioxin-like …

Animals have evolved inducible enzymatic defenses to facilitate the biotransformation and
elimination of toxic compounds encountered in the environment. The sensory component of …

Aryl hydrocarbon receptor (AHR) was initially discovered as a cellular protein involved in
mediating the detoxification of xenobiotic compounds. Extensive research in the past two …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor through which
halogenated aromatic hydrocarbons such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) …

The induction of expression of genes for xenobiotic metabolizing enzymes in response to
chemical insult is an adaptive response found in most organisms. In vertebrates, the AhR is …

The aryl hydrocarbon (Ah) receptor (AhR) is a member of the basic helix‐loop‐helix PER‐
ARNT‐SIM (PAS) transcription factor family. Consistent with the notion that PAS proteins are …

Depending on their chemical structure and properties, environmental chemicals and other
xenobiotics that enter the cell can affect cellular function by either nonselective binding to …

The effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds occur
via the aryl hydrocarbon receptor (AHR), a member of the basic helix-loop-helix-Per-ARNT …

Animals and humans are exposed each day to a multitude of chemicals in the air, water and
food. They have developed a battery of enzymes and transporters that facilitate the …