The aryl hydrocarbon receptor: a comparative perspective
ME Hahn - Comparative Biochemistry and Physiology Part C …, 1998 - Elsevier
The aryl hydrocarbon receptor (Ah receptor or AHR) is a ligand-activated transcription factor
involved in the regulation of several genes, including those for xenobiotic-metabolizing …
involved in the regulation of several genes, including those for xenobiotic-metabolizing …
The aryl hydrocarbon receptor: a key bridging molecule of external and internal chemical signals
J Tian, Y Feng, H Fu, HQ Xie, JX Jiang… - … science & technology, 2015 - ACS Publications
The aryl hydrocarbon receptor (AhR) is a highly evolutionary conserved, ligand-activated
transcription factor that is best known to mediate the toxicities of dioxins and dioxin-like …
transcription factor that is best known to mediate the toxicities of dioxins and dioxin-like …
Aryl hydrocarbon receptors: diversity and evolution
ME Hahn - Chemico-biological interactions, 2002 - Elsevier
Animals have evolved inducible enzymatic defenses to facilitate the biotransformation and
elimination of toxic compounds encountered in the environment. The sensory component of …
elimination of toxic compounds encountered in the environment. The sensory component of …
Aryl hydrocarbon receptor: Its roles in physiology
Aryl hydrocarbon receptor (AHR) was initially discovered as a cellular protein involved in
mediating the detoxification of xenobiotic compounds. Extensive research in the past two …
mediating the detoxification of xenobiotic compounds. Extensive research in the past two …
Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family
ME Hahn, SI Karchner, MA Shapiro… - Proceedings of the …, 1997 - National Acad Sciences
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor through which
halogenated aromatic hydrocarbons such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) …
halogenated aromatic hydrocarbons such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) …
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
MS Denison, SR Nagy - Annual review of pharmacology and …, 2003 - annualreviews.org
The induction of expression of genes for xenobiotic metabolizing enzymes in response to
chemical insult is an adaptive response found in most organisms. In vertebrates, the AhR is …
chemical insult is an adaptive response found in most organisms. In vertebrates, the AhR is …
A dynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins
DB Carlson, GH Perdew - Journal of biochemical and …, 2002 - Wiley Online Library
The aryl hydrocarbon (Ah) receptor (AhR) is a member of the basic helix‐loop‐helix PER‐
ARNT‐SIM (PAS) transcription factor family. Consistent with the notion that PAS proteins are …
ARNT‐SIM (PAS) transcription factor family. Consistent with the notion that PAS proteins are …
An introduction to the molecular basics of aryl hydrocarbon receptor biology
J Abel, T Haarmann-Stemmann - 2010 - degruyter.com
Depending on their chemical structure and properties, environmental chemicals and other
xenobiotics that enter the cell can affect cellular function by either nonselective binding to …
xenobiotics that enter the cell can affect cellular function by either nonselective binding to …
[HTML][HTML] Regulatory interactions among three members of the vertebrate aryl hydrocarbon receptor family: AHR repressor, AHR1, and AHR2
SI Karchner, DG Franks, WH Powell… - Journal of Biological …, 2002 - ASBMB
The effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds occur
via the aryl hydrocarbon receptor (AHR), a member of the basic helix-loop-helix-Per-ARNT …
via the aryl hydrocarbon receptor (AHR), a member of the basic helix-loop-helix-Per-ARNT …
[HTML][HTML] AhR signaling pathways and regulatory functions
L Larigot, L Juricek, J Dairou, X Coumoul - Biochimie open, 2018 - Elsevier
Animals and humans are exposed each day to a multitude of chemicals in the air, water and
food. They have developed a battery of enzymes and transporters that facilitate the …
food. They have developed a battery of enzymes and transporters that facilitate the …