Time-evolving controllability of effective connectivity networks during seizure progression
Over one third of the estimated 3 million people with epilepsy in the United States are
medication resistant. Responsive neurostimulation from chronically implanted electrodes …
medication resistant. Responsive neurostimulation from chronically implanted electrodes …
[HTML][HTML] Virtual cortical resection reveals push-pull network control preceding seizure evolution
In∼ 20 million people with drug-resistant epilepsy, focal seizures originating in
dysfunctional brain networks will often evolve and spread to surrounding tissue, disrupting …
dysfunctional brain networks will often evolve and spread to surrounding tissue, disrupting …
Emerging roles of network analysis for epilepsy
In recent years there has been increasing interest in applying network science tools to EEG
data. At the 2018 American Epilepsy Society conference in New Orleans, LA, the yearly …
data. At the 2018 American Epilepsy Society conference in New Orleans, LA, the yearly …
[HTML][HTML] Epileptic-network-based prediction and control of seizures in humans
Epilepsy is now conceptualized as a network disease. The epileptic brain network
comprises structurally and functionally connected cortical and subcortical brain regions …
comprises structurally and functionally connected cortical and subcortical brain regions …
Distributed control in a mean-field cortical network model: implications for seizure suppression
Brain electrical stimulation (BES) has long been suggested as a means of controlling
pathological brain activity. In epilepsy, control of a spatially localized source, the seizure …
pathological brain activity. In epilepsy, control of a spatially localized source, the seizure …
[HTML][HTML] Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions
Network control theory provides a framework by which neurophysiological dynamics of the
brain can be modelled as a function of the structural connectome constructed from diffusion …
brain can be modelled as a function of the structural connectome constructed from diffusion …
[HTML][HTML] Optimal control based seizure abatement using patient derived connectivity
Epilepsy is a neurological disorder in which patients have recurrent seizures. Seizures occur
in conjunction with abnormal electrical brain activity which can be recorded by the …
in conjunction with abnormal electrical brain activity which can be recorded by the …
[HTML][HTML] Weighted and directed interactions in evolving large-scale epileptic brain networks
Epilepsy can be regarded as a network phenomenon with functionally and/or structurally
aberrant connections in the brain. Over the past years, concepts and methods from network …
aberrant connections in the brain. Over the past years, concepts and methods from network …
Functional control of electrophysiological network architecture using direct neurostimulation in humans
Chronically implantable neurostimulation devices are becoming a clinically viable option for
treating patients with neurological disease and psychiatric disorders. Neurostimulation offers …
treating patients with neurological disease and psychiatric disorders. Neurostimulation offers …
[HTML][HTML] White matter network architecture guides direct electrical stimulation through optimal state transitions
Optimizing direct electrical stimulation for the treatment of neurological disease remains
difficult due to an incomplete understanding of its physical propagation through brain tissue …
difficult due to an incomplete understanding of its physical propagation through brain tissue …