[HTML][HTML] Identifying metabolic alterations in newly diagnosed small cell lung cancer patients

S Pedersen, JB Hansen, RG Maltesen, WM Szejniuk… - Metabolism Open, 2021 - Elsevier
Background Small cell lung cancer (SCLC) is a malignant disease with poor prognosis. At
the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is …

Integrated omics and gene expression analysis identifies the loss of metabolite–Metabolite correlations in small cell lung cancer

L Yu, K Li, Z Xu, G Cui, X Zhang - OncoTargets and therapy, 2018 - Taylor & Francis
Background and objective Small cell lung cancer (SCLC) is the most aggressive type of lung
carcinoma with high metastatic potential and chemoresistance upon relapse. Cancer cells …

Untargeted metabolomics and lipidomics identified four subtypes of small cell lung cancer

C Zhang, X Shang, H Wang - Metabolomics, 2022 - Springer
Introduction Small cell lung cancer (SCLC) is a heterogeneous malignancy with dismal
prognosis. However, few studies have conducted on the metabolic heterogeneity in SCLC …

Construction of a diagnostic model for small cell lung cancer combining metabolomics and integrated machine learning

X Shang, C Zhang, R Kong, C Zhao, H Wang - The Oncologist, 2024 - academic.oup.com
Background To date, no study has systematically explored the potential role of serum
metabolites and lipids in the diagnosis of small cell lung cancer (SCLC). Therefore, we …

Use of anchorchip-time-of-flight spectrometry technology to screen tumor biomarker proteins in serum for small cell lung cancer

J Du, S Yang, X Lin, L Bu, Y Nan, S Huo, W Shang - Diagnostic Pathology, 2010 - Springer
Background The purpose of this study is to discover potential biomarkers in serum for the
detection of small cell lung cancer (SCLC). Methods 74 serum samples including 30 from …

[HTML][HTML] Landscape and clinical impact of metabolic alterations in non-squamous non-small cell lung cancer

AVI Foureau, W Sha, DM Foureau… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Metabolomics studies to date have described widespread metabolic
reprogramming events during the development of non-squamous non-small cell lung cancer …

Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review

AM Elshoeibi, B Elsayed, MZ Kaleem, MR Elhadary… - Cancers, 2023 - mdpi.com
Simple Summary Our study centers on refining the diagnosis of small-cell lung cancer
(SCLC), a unique subtype with distinct therapeutic implications compared to other lung …

Emerging biomarkers and the changing landscape of small cell lung cancer

A Keogh, S Finn, T Radonic - Cancers, 2022 - mdpi.com
Simple Summary Small cell lung cancer (SCLC) is an aggressive cancer representing 15%
of all lung cancers. Unlike other types of lung cancer, treatments for SCLC have changed …

[HTML][HTML] Are there any theranostic biomarkers in small cell lung carcinoma?

F Pezzuto, F Fortarezza, F Lunardi… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Small cell lung cancer (SCLC), an aggressive lung tumour with a poor prognosis, has a high
load of somatic mutations, mainly induced by tobacco carcinogens given the strong …

High tumor metabolic activity as measured by fluorodeoxyglucose positron emission tomography is associated with poor prognosis in limited and extensive stage …

YJ Lee, A Cho, BC Cho, M Yun, SK Kim, J Chang… - Clinical cancer …, 2009 - AACR
Purpose: We investigated the prognostic effect of incorporating metabolic assessment by
18F-fluoro-2-deoxyglucose uptake on positron emission tomography/computed tomography …