This study evaluated the hypothesis that untreated and irradiated grapefruit as well as the
isolated citrus compounds naringin and limonin would protect against azoxymethane (AOM) …

Obacunone and limonin are bitter limonoids in citrus. Their modifying effects on the
development of aberrant crypt foci (ACF), the activity of detoxification enzymes, glutathione S …

Epidemiological evidence suggests that a diet abundant in fruits and vegetables may protect
against colon cancer. Bioactive compounds, including flavonoids and limonoids, have been …

The modifying effects of dietary administration of the citrus limonoids obacunone and
limonin on azoxymethane (AOM)-induced colon tumorigenesis were investigated in two …

Chemoprevention by dietary agents/supplements has emerged as a novel approach to
control various malignancies, including colorectal cancer (CRC). This study assessed …

Effects of proanthocyanidin (PA), procyanidin B-2 (B-2), and epigallocatechin gallate
(EGCG) on azoxymethane (AOM)-induced colonic preneoplastic aberrant crypt foci (ACF) …

Previous research has shown that hesperidin, a flavanone glycoside in orange juice, inhibits
colon carcinogenesis and that feeding double-strength orange juice delays the onset of …

抄録 Limonoids in citrus fruits are known to possess multiple biological functions, such as
anti-proliferative functions in human cancer cell lines. Therefore, we aimed to investigate the …

Epidemiological studies suggest that dietary limonoids and phytosterols offer protection from
certain types of cancers. Potential cancer preventive constituents of sour orange (Citrus …

The modifying effect of dietary administration of auraptene isolated from the peel of citrus
fruit (Citrus natsudaidai Hayata) on the development of azoxymethane (AOM)-induced …