Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC

H Chi, X Xie, Y Yan, G Peng, DF Strohmer… - Frontiers in …, 2022 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC), the most common head
and neck cancer, is highly aggressive and heterogeneous, resulting in variable prognoses …

Identification and validation of a novel signature based on NK cell marker genes to predict prognosis and immunotherapy response in lung adenocarcinoma by …

P Song, W Li, L Guo, J Ying, S Gao, J He - Frontiers in immunology, 2022 - frontiersin.org
Natural killer (NK) cells, the effectors of the innate immune system, have a remarkable
influence on cancer prognosis and immunotherapy. In this study, a total of 1,816 samples …

Identification and validation of neurotrophic factor-related genes signature in HNSCC to predict survival and immune landscapes

G Peng, H Chi, X Gao, J Zhang, G Song, X Xie… - Frontiers in …, 2022 - frontiersin.org
Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most
common type of cancer worldwide. Its highly aggressive and heterogeneous nature and …

[HTML][HTML] Prognostic value of novel immune-related genomic biomarkers identified in head and neck squamous cell carcinoma

Y Yao, Z Yan, S Lian, L Wei, C Zhou… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background The immune response within the tumor microenvironment plays a key role in
tumorigenesis and determines the clinical outcomes of head and neck squamous cell …

A gene signature predicting natural killer cell infiltration and improved survival in melanoma patients

J Cursons, F Souza-Fonseca-Guimaraes… - Cancer immunology …, 2019 - AACR
Natural killer (NK) cell activity is essential for initiating antitumor responses and may be
linked to immunotherapy success. NK cells and other innate immune components could be …

Immune-related gene signature for predicting the prognosis of head and neck squamous cell carcinoma

Y She, X Kong, Y Ge, P Yin, Z Liu, J Chen, F Gao… - Cancer cell …, 2020 - Springer
Abstract Background Immune-related genes (IRGs) were linked to the prognosis of head
and neck squamous cell carcinoma (HNSCC). This study aimed to identify the effects of an …

[HTML][HTML] Landscape of natural killer cell activity in head and neck squamous cell carcinoma

AJ Charap, T Enokida, R Brody… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) encompasses a set of cancers arising
from the epithelia of the upper aerodigestive tract, accounting for a significant burden of …

[HTML][HTML] The head and neck cancer immune landscape and its immunotherapeutic implications

R Mandal, Y Şenbabaoğlu, A Desrichard, JJ Havel… - JCI insight, 2016 - ncbi.nlm.nih.gov
Recent clinical trials have demonstrated a clear survival advantage in advanced head and
neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade …

Comprehensive analysis of immune cell enrichment in the tumor microenvironment of head and neck squamous cell carcinoma

I Mito, H Takahashi, R Kawabata-Iwakawa, S Ida… - Scientific Reports, 2021 - nature.com
Head and neck squamous carcinoma (HNSCC) is highly infiltrated by immune cells,
including tumor-infiltrating lymphocytes and myeloid lineage cells. In the tumor …

A pan-cancer single-cell panorama of human natural killer cells

F Tang, J Li, L Qi, D Liu, Y Bo, S Qin, Y Miao, K Yu… - Cell, 2023 - cell.com
Natural killer (NK) cells play indispensable roles in innate immune responses against tumor
progression. To depict their phenotypic and functional diversities in the tumor …