[HTML][HTML] The great escape: mRNA export through the nuclear pore complex

P De Magistris - International journal of molecular sciences, 2021 - mdpi.com
Nuclear export of messenger RNA (mRNA) through the nuclear pore complex (NPC) is an
indispensable step to ensure protein translation in the cytoplasm of eukaryotic cells. mRNA …

[HTML][HTML] Structural and functional analysis of mRNA export regulation by the nuclear pore complex

DH Lin, AR Correia, SW Cai, FM Huber… - Nature …, 2018 - nature.com
The nuclear pore complex (NPC) controls the passage of macromolecules between the
nucleus and cytoplasm, but how the NPC directly participates in macromolecular transport …

Mechanisms of nuclear mRNA export: A structural perspective

Y Xie, Y Ren - Traffic, 2019 - Wiley Online Library
Export of mRNA from the nucleus to the cytoplasm is a critical process for all eukaryotic gene
expression. As mRNA is synthesized, it is packaged with a myriad of RNA‐binding proteins …

Dynamics and kinetics of nucleo‐cytoplasmic mRNA export

A Mor, Y Shav‐Tal - Wiley Interdisciplinary Reviews: RNA, 2010 - Wiley Online Library
Activation of the gene expression pathway in eukaryotic cells results in the nuclear
transcription of mRNA molecules, many of which are destined for translation into protein by …

[HTML][HTML] Regulation of mRNA trafficking by nuclear pore complexes

A Bonnet, B Palancade - Genes, 2014 - mdpi.com
Over the last two decades, multiple studies have explored the mechanisms governing
mRNA export out of the nucleus, a crucial step in eukaryotic gene expression. During …

An agent-based model for mRNA export through the nuclear pore complex

M Azimi, E Bulat, K Weis… - Molecular biology of the …, 2014 - Am Soc Cell Biol
mRNA export from the nucleus is an essential step in the expression of every protein-coding
gene in eukaryotes, but many aspects of this process remain poorly understood. The density …

Nuclear export of mRNA: from the site of transcription to the cytoplasm

JA Erkmann, U Kutay - Experimental cell research, 2004 - Elsevier
Cellular mRNAs are produced in the nucleus and must be exported to the cytoplasm to allow
for their translation into proteins. Recruitment of export factors to nascent mRNA starts …

Molecular trafficking across the nuclear pore complex

L Gerace - Current Opinion in Cell Biology, 1992 - Elsevier
The nuclear pore complex is the gateway for protein and RNA transport between the
cytoplasm and nucleus. Recent work has characterized signals and components involved in …

Choosing the right exit: How functional plasticity of the nuclear pore drives selective and efficient mRNA export

P Bensidoun, D Zenklusen… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
The nuclear pore complex (NPC) serves as a central gate for mRNAs to transit from the
nucleus to the cytoplasm. The ability for mRNAs to get exported is linked to various upstream …

[HTML][HTML] High-resolution three-dimensional mapping of mRNA export through the nuclear pore

J Ma, Z Liu, N Michelotti, S Pitchiaya… - Nature …, 2013 - nature.com
The flow of genetic information is regulated by selective nucleocytoplasmic transport of
messenger RNA: protein complexes (mRNPs) through the nuclear pore complexes (NPCs) …