Orofacial clefts are common birth defects and can occur as isolated, nonsyndromic events or
as part of Mendelian syndromes. There is substantial phenotypic diversity in individuals with …

Cleft lip with or without cleft palate is the most common facial birth defect and it is caused by
a complex interaction between genetic and environmental factors. The purpose of this …

Clefts of the lip and/or palate (CL/P) are among the most common birth defects worldwide.
The majority are non-syndromic where CL/P occurs in isolation of other phenotypes. Where …

Orofacial clefts (OFCs)—primarily cleft lip and cleft palate—are among the most common
birth defects in all populations worldwide, and have notable population, ethnicity, and …

With an average worldwide prevalence of approximately 1.2/1000 live births, orofacial clefts
are the most common craniofacial birth defects in humans. Like other complex disorders …

Cleft lip or palate (CL/P) is a common facial defect present in 1: 700 live births and results in
substantial burden to patients. There are more than 500 CL/P syndromes described, the …

Orofacial clefts are the most common craniofacial birth defects and one of the most common
congenital malformations in humans. They require complex multidisciplinary treatment and …

Orofacial clefts (cleft lip, cleft palate) are among the most common of all major birth defects,
but very little is known about their causation. Genetic factors are thought to play a major role …

Cleft lip and palate (CLP) are birth defects that affect the upper lip and the roof of the mouth.
CLP has a multifactorial etiology, comprising both genetic and environmental factors. In this …

Objectives: Non-syndromic orofacial clefts, ie cleft lip (CL) and cleft palate (CP), are among
the most common birth defects. The goal of this study was to identify genomic regions and …