Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties
which has effects on the regulation of insulin sensitivity and insulin secretion. ALA is widely …

Type 2 Diabetes Mellitus (T2DM) which is characterised by insulin resistance, is closely
linked to the triad of glucolipotoxicity, inflammation and oxidative stress. Increased adiposity …

α-Lipoic acid (LA) is a disulfide compound that is produced in small quantities in cells, and
functions naturally as a co-enzyme in the pyruvate dehydrogenase and α-ketoglutarate …

Alpha-lipoic acid is a naturally occurring substance, essential for the function of different
enzymes that take part in mitochondria's oxidative metabolism. It is believed that alpha-lipoic …

Diabetes is a chronic metabolic disease with a high prevalence worldwide. Diabetes and
insulin resistance are associated with the development of cardiovascular and nervous …

Alpha-lipoic acid (ALA) is a substantial antioxidant in the prevention of diabetes and
diabetes complications. It can regenerate other antioxidants like vitamin E, vitamin C …

Diabetic neuropathy presents a major public health problem. It is defined by the symptoms
and signs of peripheral nerve dysfunction in diabetic patients, in whom other causes of …

α-Lipoic acid is a naturally occurring cofactor of mitochondrial dehydrogenase complexes
and a potent antioxidant. It can interchange between a reduced form and an oxidized form …

Purpose To evaluate the efficacy of alpha-lipoic acid (ALA) administration on hormonal and
metabolic parameters of obese PCOS patients. Methods A group of 32 obese PCOS patients …

α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants,
animals, and humans. It has various properties, among them great antioxidant potential and …