Flaviviruses are a genus within the Flaviviridae family of positive-strand RNA viruses and
are transmitted principally through mosquito and tick vectors. These viruses are responsible …

The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …

Most areas of the globe are endemic for at least one flavivirus, putting billions at risk for
infection. This diverse group of viral pathogens causes a range of manifestations in humans …

Highlights•No WNV and ZIKV vaccines are available for human use.•Some WNV vaccine
candidates show promising results in phase II clinical trials.•First licensed DENV vaccine …

The Flaviviridae family of RNA viruses includes numerous human disease-causing
pathogens that largely are increasing in prevalence due to continual climate change, rising …

Traditional approaches to flavivirus vaccines are still employed, while recent advancements
in biotechnology produced new approaches to vaccine design, such as recombinant live …

Dengue virus and Zika virus are mosquito-borne, single-stranded, positive-sense RNA
viruses that belong to the Flaviviridae family. Both the viruses are closely related and have …

The past 30 years has seen a dramatic global increase in human disease caused by
flaviviruses. There are approximately 60 members of the genus Flavivirus belonging to three …

Genus flavivirus comprises many important human pathogens causing public health
problems worldwide. Some flavivirus infections are characterized by a relatively high …

Lately, the global incidence of flavivirus infection has been increasing dramatically and
presents formidable challenges for public health systems around the world. Most clinically …