Background Many people with cancer experience moderate to severe pain that requires
treatment with strong opioids, such as oxycodone and morphine. Strong opioids are …

Background Pain is a common symptom with cancer, and 30% to 50% of all people with
cancer will experience moderate to severe pain that can have a major negative impact on …

Background: Oxycodone is often used as an opioid analgesic for moderate to severe cancer-
related pain, but its use varies across Europe. This systematic literature review forms the …

To evaluate the efficacy and tolerability of oxycodone in cancer-related pain, we conducted
a systematic review of randomized controlled trials. Four studies, comparing oral oxycodone …

Background This is the third updated version of a Cochrane review first published in Issue 4,
2003 of The Cochrane Library and first updated in 2007. Morphine has been used for many …

Results We found 22 systematic reviews, RCTs, or observational studies that met our
inclusion criteria. We performed a GRADE evaluation of the quality of evidence for …

PURPOSE To provide guidance on the use of opioids to manage pain from cancer or cancer
treatment in adults. METHODS A systematic review of the literature identified systematic …

Objectives To describe the evidence from Cochrane Reviews and overviews regarding the
efficacy and safety of high‐dose opioids (defined as 200 mg morphine equivalent or more …

BACKGROUND: In all recommended guidelines put forth for the treatment of cancer pain,
opioids continue to be an important part of a physician's armamentarium. Though opioids …

Background Pain is very common in patients with cancer. Opioid analgesics, including
codeine, play a significant role in major guidelines on the management of cancer pain …