El trastorn per consum d'alcohol (TCA) és una patologia cíclica caracteritzada per l'excessiu
consum d'alcohol, que inclou diverses fases d'intoxicació i abstinència. Ja que el TCA és …

Para la realización de esta tesis, la autora Sandra Fernández Rodríguez ha recibido
financiación de la Generalitat Valenciana y del Fondo Social Europeo, siendo beneficiaria …

Alcohol use disorders are chronic and highly relapsing disorders, thus alcoholic patients
have a high rate of recidivism for drug use even after long periods of abstinence. The …

Chronic ethanol intake results in brain oxidative stress and neuroinflammation, which have
been postulated to perpetuate alcohol intake and to induce alcohol relapse. The present …

Chronic ethanol intake results in brain oxidative stress and neuroinflammation, which have
been postulated to perpetuate alcohol intake and to induce alcohol relapse. The present …

Rationale Using a preclinical model based on the Alcohol Deprivation Effect (ADE), we have
reported that N-Acetylcysteine (NAC) can prevent the relapse-like drinking behaviour in long …

The development of medications to treat alcohol hangover is important for a large number of
people, especially those, who perform responsible and dangerous types of work. The …

Experimental evidence has demonstrated that the reinforcing effects of ethanol crucially
depend on the brain formation of acetaldehyde (ACD). Rationally supported by this basis …

This review article addresses the biological factors that influence:(i) the acquisition of
alcohol intake;(ii) the maintenance of chronic alcohol intake; and (iii) alcohol relapse-like …

An increase in ethanol intake is observed after a period of forced abstinence in rats, a
phenomenon known as" Alcohol Deprivation Effect"(ADE). Most of data confirm that the …