Dendritic cells loaded with exosomes derived from cancer stem cell‐enriched spheroids as a potential immunotherapeutic option
Cancer stem cells (CSCs) are responsible for therapeutic resistance and recurrence in
colorectal cancer. Despite advances in immunotherapy, the inability to specifically eradicate …
colorectal cancer. Despite advances in immunotherapy, the inability to specifically eradicate …
[HTML][HTML] Dendritic cell-derived exosomes may be a tool for cancer immunotherapy by converting tumor cells into immunogenic targets
GG Romagnoli, BB Zelante, PA Toniolo… - Frontiers in …, 2015 - frontiersin.org
Dendritic cells (DCs) have been attracting attention in cancer immunotherapy because of
their role in inducing and modulating effective immune responses. Besides the direct contact …
their role in inducing and modulating effective immune responses. Besides the direct contact …
[HTML][HTML] Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy
Exosomes are vesicles that can be secreted by many types of cell and released into the
extracellular space. Studies have found that tumor derived exosomes (TEXs) can promote …
extracellular space. Studies have found that tumor derived exosomes (TEXs) can promote …
Tumor Antigen-Primed Dendritic Cell-Derived Exosome Synergizes with Colony Stimulating Factor-1 Receptor Inhibitor by Modulating the Tumor Microenvironment …
Dendritic cell-derived exosomes (Dex) have overcome the disadvantages associated with
dendritic cell (DC) vaccines, such as cost effectiveness, stability, and sensitivity to the …
dendritic cell (DC) vaccines, such as cost effectiveness, stability, and sensitivity to the …
Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities
Y Yao, L Chen, W Wei, X Deng, L Ma, S Hao - Biochemical and biophysical …, 2013 - Elsevier
Tumor cell-derived exosomes (TEX) have been widely used to induce antitumor immune
responses in animal models and clinical trials. However, the efficiency of the antitumor …
responses in animal models and clinical trials. However, the efficiency of the antitumor …
[HTML][HTML] Comparison of exosomes derived from non-and gamma-irradiated melanoma cancer cells as a potential antigenic and immunogenic source for dendritic cell …
Cancer cells can secrete exosomes under various stressful conditions, whose functions are
involved in the delivery of various biologically active materials into host cells and/or …
involved in the delivery of various biologically active materials into host cells and/or …
[HTML][HTML] Dendritic cell-derived exosomes for cancer immunotherapy: hope and challenges
H Tian, W Li - Annals of translational medicine, 2017 - ncbi.nlm.nih.gov
Dendritic cells (DCs) are the most potent antigenpresenting cells in the human body. When
primed with antigens, DCs activate both helper and killer T cells and B cells. In the past …
primed with antigens, DCs activate both helper and killer T cells and B cells. In the past …
Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T‐lymphocyte responses and antitumour immunity
S Hao, O Bai, F Li, J Yuan, S Laferte, J Xiang - Immunology, 2007 - Wiley Online Library
Exosomes (EXO) derived from dendritic cells (DC), which express major histocompatibility
complex (MHC) and costimulatory molecules, have been used for antitumour vaccines …
complex (MHC) and costimulatory molecules, have been used for antitumour vaccines …
[HTML][HTML] Dendritic Cell-Derived Exosomes in Cancer Immunotherapy
S Luo, J Chen, F Xu, H Chen, Y Li, W Li - Pharmaceutics, 2023 - mdpi.com
Exosomes are nanoscale vesicles released by diverse types of cells for complex
intercellular communication. Numerous studies have shown that exosomes can regulate the …
intercellular communication. Numerous studies have shown that exosomes can regulate the …
Dendritic cell-derived exosomes for cancer immunotherapy: what's next?
Exosomes are nanovesicles originating from late endosomal compartments and secreted by
most living cells in ex vivo cell culture conditions. The interest in exosomes was rekindled …
most living cells in ex vivo cell culture conditions. The interest in exosomes was rekindled …