Dendritic cells loaded with exosomes derived from cancer stem cell‐enriched spheroids as a potential immunotherapeutic option

M Naseri, M Zöller, J Hadjati, R Ghods… - Journal of Cellular …, 2021 - Wiley Online Library
Cancer stem cells (CSCs) are responsible for therapeutic resistance and recurrence in
colorectal cancer. Despite advances in immunotherapy, the inability to specifically eradicate …

[HTML][HTML] Dendritic cell-derived exosomes may be a tool for cancer immunotherapy by converting tumor cells into immunogenic targets

GG Romagnoli, BB Zelante, PA Toniolo… - Frontiers in …, 2015 - frontiersin.org
Dendritic cells (DCs) have been attracting attention in cancer immunotherapy because of
their role in inducing and modulating effective immune responses. Besides the direct contact …

[HTML][HTML] Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy

H Liu, L Chen, Y Peng, S Yu, J Liu, L Wu, L Zhang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Exosomes are vesicles that can be secreted by many types of cell and released into the
extracellular space. Studies have found that tumor derived exosomes (TEXs) can promote …

Tumor Antigen-Primed Dendritic Cell-Derived Exosome Synergizes with Colony Stimulating Factor-1 Receptor Inhibitor by Modulating the Tumor Microenvironment …

A Barnwal, V Gaur, A Sengupta, W Tyagi… - ACS Biomaterials …, 2023 - ACS Publications
Dendritic cell-derived exosomes (Dex) have overcome the disadvantages associated with
dendritic cell (DC) vaccines, such as cost effectiveness, stability, and sensitivity to the …

Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities

Y Yao, L Chen, W Wei, X Deng, L Ma, S Hao - Biochemical and biophysical …, 2013 - Elsevier
Tumor cell-derived exosomes (TEX) have been widely used to induce antitumor immune
responses in animal models and clinical trials. However, the efficiency of the antitumor …

[HTML][HTML] Comparison of exosomes derived from non-and gamma-irradiated melanoma cancer cells as a potential antigenic and immunogenic source for dendritic cell …

WS Kim, DS Choi, JM Park, HY Song, HS Seo, DE Lee… - Vaccines, 2020 - mdpi.com
Cancer cells can secrete exosomes under various stressful conditions, whose functions are
involved in the delivery of various biologically active materials into host cells and/or …

[HTML][HTML] Dendritic cell-derived exosomes for cancer immunotherapy: hope and challenges

H Tian, W Li - Annals of translational medicine, 2017 - ncbi.nlm.nih.gov
Dendritic cells (DCs) are the most potent antigenpresenting cells in the human body. When
primed with antigens, DCs activate both helper and killer T cells and B cells. In the past …

Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T‐lymphocyte responses and antitumour immunity

S Hao, O Bai, F Li, J Yuan, S Laferte, J Xiang - Immunology, 2007 - Wiley Online Library
Exosomes (EXO) derived from dendritic cells (DC), which express major histocompatibility
complex (MHC) and costimulatory molecules, have been used for antitumour vaccines …

[HTML][HTML] Dendritic Cell-Derived Exosomes in Cancer Immunotherapy

S Luo, J Chen, F Xu, H Chen, Y Li, W Li - Pharmaceutics, 2023 - mdpi.com
Exosomes are nanoscale vesicles released by diverse types of cells for complex
intercellular communication. Numerous studies have shown that exosomes can regulate the …

Dendritic cell-derived exosomes for cancer immunotherapy: what's next?

S Viaud, C Théry, S Ploix, T Tursz, V Lapierre, O Lantz… - Cancer research, 2010 - AACR
Exosomes are nanovesicles originating from late endosomal compartments and secreted by
most living cells in ex vivo cell culture conditions. The interest in exosomes was rekindled …