Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain
Background Altered intestinal microbiota composition in later life is associated with
inflammaging, declining tissue function, and increased susceptibility to age-associated …
inflammaging, declining tissue function, and increased susceptibility to age-associated …
Microbiota from young mice counteracts selective age-associated behavioral deficits
The gut microbiota is increasingly recognized as an important regulator of host immunity and
brain health. The aging process yields dramatic alterations in the microbiota, which is linked …
brain health. The aging process yields dramatic alterations in the microbiota, which is linked …
Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity-and neurotransmission-related …
A D'Amato, L Di Cesare Mannelli, E Lucarini, AL Man… - Microbiome, 2020 - Springer
Background The gut-brain axis and the intestinal microbiota are emerging as key players in
health and disease. Shifts in intestinal microbiota composition affect a variety of systems; …
health and disease. Shifts in intestinal microbiota composition affect a variety of systems; …
Gut microbiota: critical controller and intervention target in brain aging and cognitive impairment
H Li, J Ni, H Qing - Frontiers in aging neuroscience, 2021 - frontiersin.org
The current trend for the rapid growth of the global aging population poses substantial
challenges for society. The human aging process has been demonstrated to be closely …
challenges for society. The human aging process has been demonstrated to be closely …
A review of the preclinical and clinical studies on the role of the gut microbiome in aging and neurodegenerative diseases and its modulation
HM Hashim, S Makpol - Frontiers in cellular neuroscience, 2022 - frontiersin.org
As the world population ages, the burden of age-related health problems grows, creating a
greater demand for new novel interventions for healthy aging. Advancing aging is related to …
greater demand for new novel interventions for healthy aging. Advancing aging is related to …
The gut microbiota is an emerging target for improving brain health during ageing
The gut microbiota plays crucial roles in maintaining the health and homeostasis of its host
throughout lifespan, including through its ability to impact brain function and regulate …
throughout lifespan, including through its ability to impact brain function and regulate …
Age drives distortion of brain metabolic, vascular and cognitive functions, and the gut microbiome
Advancing age is the top risk factor for the development of neurodegenerative disorders,
including Alzheimer's disease (AD). However, the contribution of aging processes to AD …
including Alzheimer's disease (AD). However, the contribution of aging processes to AD …
Microbiome-metabolome signatures in mice genetically prone to develop dementia, fed a normal or fatty diet
E Sanguinetti, MC Collado, VG Marrachelli… - Scientific Reports, 2018 - nature.com
Cognitive decline, obesity and gut dysfunction or microbial dysbiosis occur in association.
Our aim was to identify gut microbiota-metabolomics signatures preceding dementia in …
Our aim was to identify gut microbiota-metabolomics signatures preceding dementia in …
Multi-modal single-cell analysis reveals brain immune landscape plasticity during aging and gut microbiota dysbiosis
SM Golomb, IH Guldner, A Zhao, Q Wang, B Palakurthi… - Cell reports, 2020 - cell.com
Phenotypic and functional plasticity of brain immune cells contribute to brain tissue
homeostasis and disease. Immune cell plasticity is profoundly influenced by tissue …
homeostasis and disease. Immune cell plasticity is profoundly influenced by tissue …
The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline
AS Alsegiani, ZA Shah - Neural Regeneration Research, 2022 - journals.lww.com
Recent emerging research on intestinal microbiota and its contribution to the central nervous
system during health and disease has attracted significant attention. Age-related intestinal …
system during health and disease has attracted significant attention. Age-related intestinal …