A Pharmacovigilance Study Regarding the Risk of Antibiotic-Associated Clostridioides difficile Infection Based on Reports from the EudraVigilance Database …

BI Vintila, AM Arseniu, C Morgovan, A Butuca, M Sava… - Pharmaceuticals, 2023 - mdpi.com
The Gram-positive anaerobic bacterium Clostridioides difficile (CD) can produce intense
exotoxins, contributing to nosocomial infections, and it is the most common cause of health …

A Real-World Study on the Clinical Characteristics, Outcomes, and Relationship between Antibiotic Exposure and Clostridioides difficile Infection

BI Vintila, AM Arseniu, C Morgovan, A Butuca… - Antibiotics, 2024 - mdpi.com
Clostridioides difficile is a Gram-positive bacteria that causes nosocomial infections,
significantly impacting public health. In the present study, we aimed to describe the clinical …

Real-World Data in Pharmacovigilance Database Provides a New Perspective for Understanding the Risk of Clostridium difficile Infection Associated with …

D Li, Y Song, Z Bai, X Xi, F Liu, Y Zhang, C Qin, D Du… - Antibiotics, 2023 - mdpi.com
Antibacterial drug exposure (ADE) is a well-known potential risk factor for Clostridium
difficile infection (CDI), but it remains controversial which certain antibacterial drugs are …

[HTML][HTML] Clostridium difficile infection risk with important antibiotic classes: an analysis of the FDA adverse event reporting system

C Teng, KR Reveles… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
Introduction: Antibiotic use is an important risk factor for Clostridium difficile infection (CDI).
Prior meta-analyses have identified antibiotics and antibiotic classes that pose the greatest …

[HTML][HTML] European survey on the current surveillance practices, management guidelines, treatment pathways and heterogeneity of testing of Clostridioides difficile …

VF Viprey, G Granata, KEW Vendrik, GL Davis… - Journal of Hospital …, 2023 - Elsevier
Background Awareness and compliance with international guidelines for diagnosis and
clinical management of Clostridioides difficile infection (CDI) are unknown. Aim To compare …

[HTML][HTML] Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review

LSM Kuula, KM Viljemaa, JT Backman, M Blom - PLoS One, 2019 - journals.plos.org
Background and objectives Adverse events (AEs) associated with the use of fluoroquinolone
antimicrobials include Clostridium difficile associated diarrhea (CDAD), liver injury and …

[HTML][HTML] Epidemiology of Clostridioides difficile infections, France, 2010 to 2017

M Colomb-Cotinat, L Assouvie, J Durand… - …, 2019 - eurosurveillance.org
Background Clostridioides difficile is a leading cause of healthcare-associated diarrhoea in
middle and high-income countries. Up to 2018, there has been no systematic, annual …

Hospital-level high-risk antibiotic use in relation to hospital-associated Clostridioides difficile infections: retrospective analysis of 2016–2017 data from US hospitals

YP Tabak, A Srinivasan, CY Kalvin… - Infection Control & …, 2019 - cambridge.org
Objective: Antibiotics are widely used by all specialties in the hospital setting. We evaluated
previously defined high-risk antibiotic use in relation to Clostridioides difficile infections …

Antimicrobial susceptibility of Clostridioides difficile isolated from diarrhoeal stool specimens of Canadian patients: summary of results from the Canadian …

JA Karlowsky, HJ Adam, MR Baxter… - Journal of …, 2020 - academic.oup.com
Objectives To summarize data generated by the Canadian Clostridioides difficile (CAN-
DIFF) surveillance study from 2013 to 2017. Methods Isolates of C. difficile (n= 2158) were …

Evaluation of Clostridium difficile-associated diarrhea with a drug formulary change in preferred fluoroquinolones

MA Walbrown, SL Aspinall, NK Bayliss… - Journal of Managed …, 2008 - jmcp.org
BACKGROUND: Recent publications report that gatifloxacin might be associated with a
greater incidence of Clostridium difficile-associated diarrhea (C. difficile, CDAD) than are …