Levosimendan ameliorates the scopolamine induced cognitive impairment via modulating pCREB/BDNF expression, cholinergic neurotransmission and …
AS Kolusu, GS Ganesh, M Nagabhairava… - 2023 - researchsquare.com
Levosimendan, an inotropic drug that potentiates ATP-dependent K+ channel and sensitise
troponin-C for calcium. It has positive effects in neurodegenerative diseases like Parkinson's …
troponin-C for calcium. It has positive effects in neurodegenerative diseases like Parkinson's …
Levosimendan prevents memory impairment induced by diabetes in rats: role of oxidative stress
AM Rababa'h, KH Alzoubi, S Baydoun… - Current Alzheimer …, 2019 - ingentaconnect.com
Background: Levosimendan is a calcium sensitizer and phosphodiesterase inhibitor that has
potent antioxidant and anti-inflammatory activities. Objectives: The aim of the current study is …
potent antioxidant and anti-inflammatory activities. Objectives: The aim of the current study is …
Levosimendan enhances memory through antioxidant effect in rat model: behavioral and molecular study
AM Rababa'h, KH Alzoubi, A Atmeh - Behavioural Pharmacology, 2018 - journals.lww.com
Impairment of learning and memory has been associated with accumulation of reactive
oxygen species in the body. It has also been found that antioxidants enhance learning and …
oxygen species in the body. It has also been found that antioxidants enhance learning and …
The effect of levosimendan on two distinct rodent models of Parkinson's disease
AN Abuirmeileh, KH Alzoubi… - Current Alzheimer …, 2020 - ingentaconnect.com
Background: Parkinson's disease (PD) is a common neurodegenerative disorder that is
characterized by motor symptoms related to the deficiency in dopamine levels, and cognitive …
characterized by motor symptoms related to the deficiency in dopamine levels, and cognitive …
Levosimendan exerts anticonvulsant properties against PTZ-induced seizures in mice through activation of nNOS/NO pathway: role for KATP channel
M Gooshe, M Tabaeizadeh, AR Aleyasin, P Mojahedi… - Life Sciences, 2017 - Elsevier
Aims Although approving new anticonvulsants was a major breakthrough in the field of
epilepsy control, so far we have met limited success in almost one third of patients suffering …
epilepsy control, so far we have met limited success in almost one third of patients suffering …
[PDF][PDF] Neurocognitive and neuroprotective potential of Mimusops elengi in mice model of scopolamine-induced amnesia
J Rajangam, DP Parthasaradhi, M Kotakonda… - Drug …, 2023 - researchgate.net
The study was aimed to assess the cognitive and protective potential of methanol extract of
Mimusops elengi bark (MEME-B) and flowers (MEME-F) against a mice model of the …
Mimusops elengi bark (MEME-B) and flowers (MEME-F) against a mice model of the …
Levosimendan Ameliorates Hypoxia-Induced Brain Injury in Rats by Modulating PTEN/Akt Signaling Pathway-Mediated Ferroptosis
W Meng, C Shu, H Gao - Discovery medicine, 2024 - pubmed.ncbi.nlm.nih.gov
Background Levosimendan (Levo) is a drug commonly used to treat heart failure. Recent
studies have suggested that Levo may have neuroprotective effects, but it is still unknown …
studies have suggested that Levo may have neuroprotective effects, but it is still unknown …
Neuroprotective effects of matrine on scopolamine-induced amnesia via inhibition of AChE/BuChE and oxidative stress
K Sun, Y Bai, R Zhao, Z Guo, X Su, P Li, P Yang - Metabolic Brain Disease, 2019 - Springer
The present study was designed to evaluate the effects of matrine (MAT) on scopolamine
(SCOP)-induced learning and memory impairment. After successive oral administration of …
(SCOP)-induced learning and memory impairment. After successive oral administration of …
[HTML][HTML] Ranuncoside's attenuation of scopolamine-induced memory impairment in mice via Nrf2 and NF-ĸB signaling
HS Salahuddin, S Attaullah, SA Shah, SU Khan… - Saudi Pharmaceutical …, 2023 - Elsevier
Scopolamine is a well-known pharmacological agent responsible for causing memory
impairment in animals, as well as oxidative stress and neuroinflammation inducer which …
impairment in animals, as well as oxidative stress and neuroinflammation inducer which …
Neuroprotective Effect of Marrubium vulgare Extract in Scopolamine-Induced Cognitive Impairment in Rats: Behavioral and Biochemical Approaches
Simple Summary Cognitive deficits, including spatial working and recognition memory
impairment, are a common feature of Alzheimer's disease with current therapies offering …
impairment, are a common feature of Alzheimer's disease with current therapies offering …
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