[HTML][HTML] Genotype-Guided Selection of Antiplatelet Therapy: The Evidence Moves East

LH Cavallari, F Franchi - Cardiovascular Interventions, 2023 - jacc.org
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is recommended
following percutaneous coronary intervention (PCI) to reduce the risk for major adverse …

[HTML][HTML] Genotype-guided antiplatelet therapy in patients with coronary artery disease

F Franchi, F Rollini - Cardiovascular Interventions, 2021 - jacc.org
P2Y12 receptor inhibitor (clopidogrel, prasugrel, or ticagrelor) represents the standard of
care for the prevention of ischemic events in patients with coronary artery disease, in …

Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world …

NA Limdi, LH Cavallari, CR Lee, WB Hillegass… - The …, 2020 - nature.com
Current guidelines recommend dual antiplatelet therapy (DAPT) consisting of aspirin and a
P2Y12 inhibitors following percutaneous coronary intervention (PCI). CYP2C19 genotype …

Precision Antiplatelet Therapy after Percutaneous Coronary Intervention (Precision PCI) Registry–Informing optimal antiplatelet strategies

LH Cavallari, CR Lee, F Franchi… - Clinical and …, 2024 - Wiley Online Library
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor (clopidogrel,
prasugrel, or ticagrelor) is indicated after percutaneous coronary intervention (PCI) to reduce …

Meta-Analysis of the Efficacy and Safety of Genotype-Guided Strategy for Selection of P2Y12 Inhibitors in Coronary Artery Disease

S Nazir, KR Ahuja, A Elzanaty, NJ Patel… - American Journal of …, 2020 - ajconline.org
Despite the development of newer and more potent antiplatelet medications, clopidogrel
remained the most prescribed P2Y12 inhibitor after percutaneous coronary intervention …

Dual Antiplatelet Therapy in Percutaneous Coronary Intervention: Exploring the Role of Genotype-Guided Therapy in Reducing Readmission Rates

M Comanici, SG Raja - American Journal of Cardiology, 2023 - ajconline.org
Dual antiplatelet therapy comprising aspirin and a P2Y12 receptor inhibitor is widely used
for patients who underwent percutaneous coronary intervention (PCI). 1 Although …

How is pharmacogenetics changing clinical trial design for percutaneous coronary intervention?

M Galli, DJ Angiolillo - Expert Review of Clinical Pharmacology, 2023 - Taylor & Francis
Oral P2Y12 inhibitors represent the cornerstone of treatment for patients undergoing
percutaneous coronary interventions (PCI)[1]. In patients undergoing PCI, oral P2Y12 …

[PDF][PDF] Clopidogrel versus ticagrelor or prasugrel after primary PCI according to CYP2C19 genotype

TO Bergmeijer, DMF Claassens, GJA Vos… - Antiplatelet treatment in … - researchgate.net
Background Guidelines favour ticagrelor or prasugrel over clopidogrel in patients with
myocardial infarction. However, the POPular Genetics trial (Patient Outcome After Primary …

Genotype-Guided Antiplatelet Therapy: JACC Review Topic of the Week

WWA van den Broek, BS Ingraham, NL Pereira… - Journal of the American …, 2024 - jacc.org
The clinical efficacy and safety of antiplatelet agents vary among patients. Consequently,
some patients are at increased risk of recurrent ischemic events during treatment. This …

[HTML][HTML] CYP2C19 Genotyping in Percutaneous Coronary Intervention-Treated Patients: Ready for Prime Time?

D Sibbing, L Gross - JACC: Cardiovascular Interventions, 2018 - jacc.org
Dual antiplatelet treatment (DAPT) with aspirin and a P2Y12 receptor inhibitor is the current
mainstay of treatment for patients undergoing percutaneous coronary intervention (PCI) …