Production and Evaluation of Ag85B:HspX:hFcγ1 Immunogenicity as an Fc Fusion Recombinant Multi-Stage Vaccine Candidate Against Mycobacterium tuberculosis
An urgent need is to introduce an effective vaccine against Mycobacterium tuberculosis (M.
tb) infection. In the present study, a multi-stage M. tb immunodominant Fcγ1 fusion protein …
tb) infection. In the present study, a multi-stage M. tb immunodominant Fcγ1 fusion protein …
Fused Mycobacterium tuberculosis multi-stage immunogens with an Fc-delivery system as a promising approach for the development of a tuberculosis vaccine
Tuberculosis (TB) remains a major health problem worldwide. Currently, the Bacilli Calmette-
Guérin (BCG) is the only available licensed TB vaccine, which has low efficacy in protection …
Guérin (BCG) is the only available licensed TB vaccine, which has low efficacy in protection …
Mycobacterium tuberculosis Ag85b: hfcγ1 recombinant fusion protein as a selective receptor-dependent delivery system for antigen presentation
MKZ Babaki, M Taghiabadi, S Soleimanpour… - Microbial …, 2019 - Elsevier
Introducing an effective vaccine for tuberculosis (TB) is an urgent need. Mycobacterium
tuberculosis (Mtb) Ag85 complex is suggested for making protective immunodominant …
tuberculosis (Mtb) Ag85 complex is suggested for making protective immunodominant …
Construction and immunogenicity of a new Fc-based subunit vaccine candidate against Mycobacterium tuberculosis
A Kebriaei, M Derakhshan, Z Meshkat… - Molecular biology …, 2016 - Springer
As an ancient disease, tuberculosis (TB) is a major global health threat. Therefore, there is
an urgent need for an effective and safe anti-TB vaccine. In the current study, a delivery …
an urgent need for an effective and safe anti-TB vaccine. In the current study, a delivery …
Construction and evaluation of a multistage Mycobacterium tuberculosis subunit vaccine candidate Mtb10. 4–HspX
H Niu, L Hu, Q Li, Z Da, B Wang, K Tang, Q Xin, H Yu… - Vaccine, 2011 - Elsevier
To search for more effective vaccines to enhance the immunogenicity and protective efficacy
of Mycobacterium bovis Bacille Calmette-Guerin (BCG) and to control or even eradicate …
of Mycobacterium bovis Bacille Calmette-Guerin (BCG) and to control or even eradicate …
Cloning, expression, and immunogenicity of novel fusion protein of Mycobacterium tuberculosis based on ESAT-6 and truncated C-terminal fragment of HSP70
M Tebianian, AZ Hoseini, SM Ebrahimi… - Biologicals, 2011 - Elsevier
Tuberculosis (TB) remains as a major public health problem worldwide. Identification and
selection of immunodominant antigens of Mycobacterium tuberculosis (MTB), capable of …
selection of immunodominant antigens of Mycobacterium tuberculosis (MTB), capable of …
The development and preliminary evaluation of a new Mycobacterium tuberculosis vaccine comprising Ag85b, HspX and CFP-10:ESAT-6 fusion protein with CpG …
L Chen, M Xu, ZY Wang, BW Chen… - FEMS Immunology & …, 2010 - academic.oup.com
Ag85b and HspX of Mycobacterium tuberculosis (Mtb)(H37Rv) were expressed and purified
in this study. These two proteins were combined with another fusion protein CFP-10: ESAT-6 …
in this study. These two proteins were combined with another fusion protein CFP-10: ESAT-6 …
Fusion protein Ag85B-MPT64190–198-Mtb8. 4 has higher immunogenicity than Ag85B with capacity to boost BCG-primed immunity against Mycobacterium …
Y Luo, B Wang, L Hu, H Yu, Z Da, W Jiang, N Song… - Vaccine, 2009 - Elsevier
Tuberculosis (TB) remains a major infectious disease worldwide despite chemotherapy and
BCG vaccine. The efficacy of the current TB vaccine BCG varies from 0 to 80%. New …
BCG vaccine. The efficacy of the current TB vaccine BCG varies from 0 to 80%. New …
Fc-based delivery system enhances immunogenicity of a tuberculosis subunit vaccine candidate consisting of the ESAT-6: CFP-10 complex
Tuberculosis (TB) remains a major global health threat despite chemotherapy and Bacilli
Calmette–Guérin (BCG) vaccination. Therefore, a safer and more effective vaccine against …
Calmette–Guérin (BCG) vaccination. Therefore, a safer and more effective vaccine against …
Immunogenicity and Protective Efficacy of a Fusion Protein Vaccine Consisting of Antigen Ag85B and HspX against Mycobacterium tuberculosis Infection in Mice
Q Li, H Yu, Y Zhang, B Wang, W Jiang… - Scandinavian …, 2011 - Wiley Online Library
Subunit vaccines have the potential advantage to boost Mycobacterium bovis Bacillus
Calmette‐Guérin (BCG)‐primed immunity in adults. However, most candidates are antigens …
Calmette‐Guérin (BCG)‐primed immunity in adults. However, most candidates are antigens …
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