Thrombolysis: newer thrombolytic agents and their role in clinical medicine

TK Nordt, C Bode - Heart, 2003 - heart.bmj.com
Reperfusion treatment in acute myocardial infarction represents the main indication for
thrombolytic therapy. The most common thrombolytic agents have been streptokinase (first …

Thrombolytics and myocardial infarction

V Kunadian, CM Gibson - Cardiovascular therapeutics, 2012 - Wiley Online Library
Coronary artery disease is the single leading cause of death in the United States. Occlusion
of the coronary artery was identified to be the cause of myocardial infarction almost a century …

Thrombolytic therapy

D Collen - Thrombosis and haemostasis, 1997 - thieme-connect.com
Cardiovascular diseases, comprising acute myocardial infarction (AMI), stroke and venous
thromboembolism have, as their immediate underlying cause, thrombosis of critically …

The future of thrombolysis in the treatment of acute myocardial infarction

C Bode, MS Runge, RW Smalling - European heart journal, 1996 - academic.oup.com
The ability of thrombolytic therapy to lower mortality in patients with acute myocardial
infarction was first demonstrated in 1986 by the Gruppo Italiano per lo Studio della …

Tenecteplase: a review

L Davydov, JWM Cheng - Clinical therapeutics, 2001 - Elsevier
Background: Certain shortcomings of the available thrombolytic agents have prompted the
search for a more fibrin specific fibrinolytic agent with a longer half-life. Such properties …

Thrombolytic therapy for acute myocardial infarction: a review

CB Granger, RM Califf, EJ Topol - Drugs, 1992 - Springer
In the past 10 years, thrombolytics have become standard therapy for acute myocardial
infarction. Although the ability of streptokinase to lyse clot was first recognised in the 1930s …

Thrombolytic therapy: A review of its use in acute myocardial infarction

ED Bizjak, VF Mauro - Annals of Pharmacotherapy, 1998 - journals.sagepub.com
OBJECTIVE: To review the literature on the use of thrombolytic agents in the
pharmacotherapeutic management of acute myocardial infarction (AMI). DATA SOURCE …

New developments in thrombolytic therapy

DC Collen, HK Gold - Thrombosis research, 1990 - Elsevier
Thrombotic complications of cardiovascular disease are a main cause of death and disability
and, consequently, thrombolysis could favorably influence the outcome of such life …

Comparative efficacy of thrombolytics in acute myocardial infarction: a systematic review

Y Dundar, R Hill, R Dickson, T Walley - Qjm, 2003 - academic.oup.com
Background: The comparative clinical effectiveness of new (reteplase, tenecteplase) vs.
older (alteplase, streptokinase) thrombolytic agents in the treatment of acute myocardial …

Fibrin-selective thrombolytic therapy for acute myocardial infarction

D Collen - Circulation, 1996 - Am Heart Assoc
Thrombolytic therapy of acute myocardial infarction is based on the premise that coronary
artery thrombosis is its proximate cause. Rupture of atheromatous plaque leads to occlusive …