Wnt signaling transduces evolutionarily conserved pathways which play important roles in
initiating and regulating a diverse range of cellular activities, including cell proliferation …

Many cancers have similar aberrations in various signaling cascades with crucial roles in
cellular proliferation, differentiation, and morphogenesis. Dysregulation of signal cascades …

WNT signalling has been studied primarily in developing embryos, in which cells respond to
WNTs in a context-dependent manner through changes in survival and proliferation, cell fate …

Wnt proteins are a large family of secreted glycoproteins. Wnt proteins bind to the Frizzled
receptors and LRP5/6 co-receptors, and through stabilizing the critical mediator β-catenin …

The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication
system that is important for stem cell renewal, cell proliferation and cell differentiation both …

The functional versatility of Wnt/β-catenin signaling can be seen by its ability to act in stem
cells of the embryo and of the adult as well as in cancer stem cells. During embryogenesis …

The canonical WNT/β-catenin signaling pathway governs a myriad of biological processes
underlying the development and maintenance of adult tissue homeostasis, including …

The WNT pathway is a pleiotropic signaling pathway that controls developmental processes,
tissue homeostasis, and cancer. The WNT pathway is commonly mutated in many cancers …

Wnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical
for a variety of physiological processes of an organism's body, including stem cell …

Wnt proteins are a large family of secreted glycoproteins that activate signal transduction
pathways to control a wide variety of cellular processes suchas determination of cell fate …