Genetic studies of ankylosing spondylitis (AS) have, over the past decade, provided major
insights into the etiopathogenesis of the disease that have led to major therapeutic …

While twin studies have previously demonstrated high heritability of susceptibility to
ankylosing spondylitis (AS), it is only recently that the involvement of genetic factors in …

Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and
sacroiliac joints. It causes significant disability and is associated with a number of other …

Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic
and environmental. AS patients are predominantly young men, and the disease is …

Objective To assess the role of genes and the environment in determining the severity of
ankylosing spondylitis. Methods One hundred seventy‐three families with> 1 case of …

Ankylosing spondylitis (AS), an immune-mediated arthritis, is the prototypic member of a
group of conditions known as spondyloarthropathies that also includes reactive arthritis …

There is strong evidence from twin and family studies indicating that a substantial proportion
of the heritability of susceptibility to ankylosing spondylitis (AS) and its clinical manifestations …

Ankylosing spondylitis (AS) is the prototypic form of axial spondyloarthritis (axSpA). It is
highly heritable, with studies conducted in twins and in unrelated cases and controls …

Objective Ankylosing spondylitis (AS) affects 0.25–1.0% of the population, and its etiology is
incompletely understood. Susceptibility to this highly familial disease (λs= 58) is primarily …

Objective To localize the regions containing genes that determine susceptibility to
ankylosing spondylitis (AS). Methods One hundred five white British families with 121 …