Gene expression in the human mammary epithelium during lactation: the milk fat globule transcriptome

PD Maningat, P Sen, M Rijnkels… - Physiological …, 2009 - journals.physiology.org
The molecular physiology underlying human milk production is largely unknown because of
limitations in obtaining tissue samples. Determining gene expression in normal lactating …

RNA sequencing of the human milk fat layer transcriptome reveals distinct gene expression profiles at three stages of lactation

DG Lemay, OA Ballard, MA Hughes, AL Morrow… - PloS one, 2013 - journals.plos.org
Aware of the important benefits of human milk, most US women initiate breastfeeding but
difficulties with milk supply lead some to quit earlier than intended. Yet, the contribution of …

Analysis of human breast milk cells: gene expression profiles during pregnancy, lactation, involution, and mastitic infection

JA Sharp, C Lefèvre, A Watt, KR Nicholas - Functional & Integrative …, 2016 - Springer
The molecular processes underlying human milk production and the effects of mastitic
infection are largely unknown because of limitations in obtaining tissue samples …

Sequencing the transcriptome of milk production: milk trumps mammary tissue

DG Lemay, RC Hovey, SR Hartono, K Hinde… - BMC genomics, 2013 - Springer
Background Studies of normal human mammary gland development and function have
mostly relied on cell culture, limited surgical specimens, and rodent models. Although RNA …

Comparison of five different RNA sources to examine the lactating bovine mammary gland transcriptome using RNA-Sequencing

A Cánovas, G Rincón, C Bevilacqua, A Islas-Trejo… - Scientific reports, 2014 - nature.com
The objective of this study was to examine five different sources of RNA, namely mammary
gland tissue (MGT), milk somatic cells (SC), laser microdissected mammary epithelial cells …

[PDF][PDF] Regulation of gene expression in human mammary epithelium: effect of breast pumping

PD Maningat, P Sen, AL Sunehag… - Journal of …, 2007 - researchgate.net
Little is known of the molecular regulation of human milk production because of limitations in
obtaining mammary tissue from lactating women. Our objectives were to evaluate whether …

Gene networks driving bovine milk fat synthesis during the lactation cycle

M Bionaz, JJ Loor - BMC genomics, 2008 - Springer
Background The molecular events associated with regulation of milk fat synthesis in the
bovine mammary gland remain largely unknown. Our objective was to study mammary …

Gene expression in breastmilk cells is associated with maternal and infant characteristics

AJ Twigger, AR Hepworth, C Tat Lai, E Chetwynd… - Scientific reports, 2015 - nature.com
Breastmilk is a rich source of cells with a heterogeneous composition comprising early-stage
stem cells, progenitors and more differentiated cells. The gene expression profiles of these …

Transcriptomic profiles of the bovine mammary gland during lactation and the dry period

W Dai, Y Zou, RR White, J Liu, H Liu - Functional & integrative genomics, 2018 - Springer
The initiation and maintenance of lactation are complex phenomena governed by
biochemical and endocrine processes in the mammary gland (MG). Although DNA-based …

[HTML][HTML] Validation of RNA isolated from milk fat globules to profile mammary epithelial cell expression during lactation and transcriptional response to a bacterial …

P Brenaut, R Bangera, C Bevilacqua, E Rebours… - Journal of Dairy …, 2012 - Elsevier
Mastitis, an inflammation of the mammary gland, is the most costly infectious disease of dairy
ruminants worldwide. Although it receives considerable attention, the early steps of the host …