Broken detailed balance and non-equilibrium dynamics in living systems: a review

FS Gnesotto, F Mura, J Gladrow… - Reports on Progress in …, 2018 - iopscience.iop.org
Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce
broken detailed balance at the molecular scale. This molecular scale breaking of detailed …

Broken detailed balance at mesoscopic scales in active biological systems

C Battle, CP Broedersz, N Fakhri, VF Geyer, J Howard… - Science, 2016 - science.org
Systems in thermodynamic equilibrium are not only characterized by time-independent
macroscopic properties, but also satisfy the principle of detailed balance in the transitions …

Nonequilibrium thermodynamics in cell biology: Extending equilibrium formalism to cover living systems

X Fang, J Wang - Annual review of biophysics, 2020 - annualreviews.org
We discuss new developments in the nonequilibrium dynamics and thermodynamics of
living systems, giving a few examples to demonstrate the importance of nonequilibrium …

Nonequilibrium physics in biology

X Fang, K Kruse, T Lu, J Wang - Reviews of Modern Physics, 2019 - APS
Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

How molecular motors extract order from chaos (a key issues review)

PM Hoffmann - Reports on Progress in Physics, 2016 - iopscience.iop.org
Molecular motors are the workhorses of living cells. Seemingly by'magic', these molecules
are able to complete purposeful tasks while being immersed in a sea of thermal chaos …

The free-energy cost of accurate biochemical oscillations

Y Cao, H Wang, Q Ouyang, Y Tu - Nature physics, 2015 - nature.com
Oscillations within the cell regulate the timing of many important life cycles. However, in this
noisy environment, oscillations can be highly inaccurate owing to phase fluctuations. It …

Estimating entropy production from waiting time distributions

DJ Skinner, J Dunkel - Physical review letters, 2021 - APS
Living systems operate far from thermal equilibrium by converting the chemical potential of
ATP into mechanical work to achieve growth, replication, or locomotion. Given time series …

Power spectrum of out-of-equilibrium forces in living cells: amplitude and frequency dependence

F Gallet, D Arcizet, P Bohec, A Richert - Soft matter, 2009 - pubs.rsc.org
Living cells exhibit an important out-of-equilibrium mechanical activity, mainly due to the
forces generated by molecular motors, acting individually or collectively on the cytoskeleton …

Topologically protected modes in non-equilibrium stochastic systems

A Murugan, S Vaikuntanathan - Nature communications, 2017 - nature.com
Non-equilibrium driving of biophysical processes is believed to enable their robust
functioning despite the presence of thermal fluctuations and other sources of disorder. Such …

Feedback-tracking microrheology in living cells

K Nishizawa, M Bremerich, H Ayade, CF Schmidt… - Science …, 2017 - science.org
Living cells are composed of active materials, in which forces are generated by the energy
derived from metabolism. Forces and structures self-organize to shape the cell and drive its …