Maternal immunity and the natural history of congenital human cytomegalovirus infection

WJ Britt - Viruses, 2018 - mdpi.com
Congenital human cytomegalovirus (HCMV) is the most common viral infection of the
developing fetus, and a significant cause of neurodevelopmental abnormalities in infants …

Controversies in the natural history of congenital human cytomegalovirus infection: the paradox of infection and disease in offspring of women with immunity prior to …

W Britt - Medical microbiology and immunology, 2015 - Springer
Human cytomegalovirus (HCMV) is the most common virus infection in the developing fetus.
A fraction of infants infected in utero develop significant life-threatening and organ …

Congenital human cytomegalovirus infection and the enigma of maternal immunity

WJ Britt - Journal of virology, 2017 - Am Soc Microbiol
Human cytomegalovirus (HCMV) is the most common viral infection acquired by the
developing human fetus and can result in damage to the developing central nervous system …

Cytomegalovirus in the neonate: immune correlates of infection and protection

MR Schleiss - Journal of Immunology Research, 2013 - Wiley Online Library
Fetal and neonatal infections caused by human cytomegalovirus (CMV) are important
causes of morbidity and occasional mortality. Development of a vaccine against congenital …

Advancing our understanding of protective maternal immunity as a guide for development of vaccines to reduce congenital cytomegalovirus infections

SR Permar, MR Schleiss, SA Plotkin - Journal of virology, 2018 - Am Soc Microbiol
Human cytomegalovirus (HCMV) is the most common congenitally transmitted pathogen
worldwide, impacting an estimated 1 million newborns annually. Congenital HCMV (cCMV) …

Progress toward development of a vaccine against congenital cytomegalovirus infection

MR Schleiss, SR Permar, SA Plotkin - Clinical and Vaccine …, 2017 - Am Soc Microbiol
ABSTRACT A vaccine against congenital human cytomegalovirus (CMV) infection is a major
public health priority. Congenital CMV causes substantial long-term morbidity, particularly …

Nonhuman primate models of intrauterine cytomegalovirus infection

PA Barry, KM Lockridge, S Salamat, SP Tinling… - ILAR …, 2006 - academic.oup.com
Congenital human cytomegalovirus (HCMV) infection has long been recognized as a threat
to the developing fetus, even though studies have shown that only a subset of congenital …

Congenital cytomegalovirus infection: review of the epidemiology and outcome

MA Gaytant, EAP Steegers… - Obstetrical & …, 2002 - journals.lww.com
Cytomegalovirus (CMV) is one of the most common viral causes of congenital infection. A
future decision to lower its incidence by vaccination will depend on epidemiological …

Nonprimate models of congenital cytomegalovirus (CMV) infection: gaining insight into pathogenesis and prevention of disease in newborns

MR Schleiss - ILAR journal, 2006 - academic.oup.com
Congenital and perinatal infections with cytomegalovirus (CMV) are responsible for
considerable short-and long-term morbidity in infants. CMV is the most common congenital …

Maternal cytomegalovirus immune status and hearing loss outcomes in congenital cytomegalovirus-infected offspring

GJ Demmler-Harrison, JA Miller… - PloS one, 2020 - journals.plos.org
Objectives The purpose of this study is to determine the relationship between maternal
primary and recurrent CMV infection during pregnancy, symptoms at birth in the newborn …