Centromeres are essential genetic elements that enable spindle microtubule attachment for
chromosome segregation during mitosis and meiosis. While this function is preserved …

The centromere is perhaps the most iconic feature on a eukaryotic chromosome. An amateur
enthusiast equipped with a light microscope can easily identify the center of each …

Centromeres mediate the faithful segregation of eukaryotic chromosomes. Yet they display a
remarkable range in size and complexity across eukaryotes, from∼ 125 bp in budding yeast …

Highlights•Cortical CDC42 signaling leads to asymmetric tyrosination of meiosis I spindle
microtubules.•Centromeric DNA expansion recruits more CenH3, increases centromere …

Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

Centromeres are important because they are necessary for the correct transmission of
chromosomes in eukaryotes. With the kinetochore, they form the link between two well …

Centromeres play a key role in the maintenance of genome stability to prevent
carcinogenesis and diseases. They are specialized chromosome loci essential to ensure …

Centromeric repetitive DNA is the largest missing piece of the Human Genome Project.
Rather than being necessary or sufficient to specify the site of mitotic spindle attachment to …

Centromeres are specialized chromosomal regions that recruit kinetochore proteins and
mediate spindle microtubule attachment to ensure faithful chromosome segregation during …

Centromeres are the chromosomal domains required to ensure faithful transmission of the
genome during cell division. They have a central role in preventing aneuploidy, by …