Virulence is the outcome of an interaction between the host and a microbe and is
characterized by a large array of opposing reactions operating at the host-pathogen …

Laccase is an important virulence factor for the human pathogen, Cryptococcus neoformans.
In this review, we examine the structural, biological and genetic features of the enzyme and …

Laccase is a major virulence factor of the pathogenic fungus Cryptococcus neoformans,
which afflicts both immunocompetent and immunocompromised individuals. In the present …

While laccase of Cryptococcus neoformans is implicated in the virulence of the organism,
our recent studies showing absence of melanin in the infected mouse brain has led us to a …

To assess the relationship between melanin production by Cryptococcus neoformans and
virulence on a molecular basis, we asked:(a) is CNLAC1, the laccase structural gene of C …

C. neoformans is a leading cause of fatal mycosis linked to CNS dissemination. Laccase,
encoded by the LAC1 gene, is an important virulence factor implicated in brain …

Cryptococcus neoformans is an environmental yeast that is a leading cause of fatal mycosis
in AIDS patients and a major cause of meningoencephalitis and CNS-related mortality …

Laccase is a major virulence factor required for infection caused by the human pathogenic
yeast Cryptococcus neoformans. However, cellular processes involved in the regulation and …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …