Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2019 - Elsevier
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …

Adipose tissue, obesity and non-alcoholic fatty liver disease.

SA Polyzos, J Kountouras… - Minerva endocrinologica, 2016 - europepmc.org
The association of obesity with non-alcoholic fatty liver disease (NAFLD) has been
established. Obesity has been linked not only to initial stages of the disease, ie, simple …

Obesity and the liver: nonalcoholic fatty liver disease

SWP Koppe - Translational Research, 2014 - Elsevier
The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) parallels the rise of
obesity and its complications. NAFLD is a common cause of cirrhosis and a leading …

Nonalcoholic fatty liver disease: hepatic manifestation of obesity and the metabolic syndrome.

H Boppidi, SR Daram - Postgraduate medicine, 2008 - europepmc.org
Obesity is currently a worldwide epidemic, and will likely only increase in prevalence in the
coming years. The incidence of the metabolic syndrome (MetS) seems to be paralleling …

Non‐alcoholic fatty liver disease from pathogenesis to management: an update

G Musso, R Gambino, M Cassader - Obesity Reviews, 2010 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD), the most common chronic liver disease in the
Western world, is tightly associated with obesity and metabolic syndrome. NAFLD entails an …

Non-alcoholic fatty liver disease: pathophysiological concepts and treatment options

C Grander, F Grabherr, H Tilg - Cardiovascular Research, 2023 - academic.oup.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is continually increasing due to
the global obesity epidemic. NAFLD comprises a systemic metabolic disease accompanied …

Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

P Dietrich, C Hellerbrand - Best practice & research Clinical …, 2014 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is now recognized as the most common cause of
chronic liver disease worldwide. Its prevalence has increased to more than 30% of adults in …

Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss

S Pouwels, N Sakran, Y Graham, A Leal, T Pintar… - BMC endocrine …, 2022 - Springer
Given the increasing prevalence of diabetes and obesity worldwide, the deleterious effects
of non-alcoholic fatty liver disease (NAFLD) are becoming a growing challenge for public …

Anti-obesity medications for the management of nonalcoholic fatty liver disease

SA Polyzos, DG Goulis, O Giouleme… - Current Obesity …, 2022 - Springer
Abstract Purpose of Review Obesity is closely associated with nonalcoholic fatty liver
disease (NAFLD), a highly prevalent disease without any approved medication. The aim of …

New therapeutic strategies in nonalcoholic fatty liver disease: A focus on promising drugs for nonalcoholic steatohepatitis

N Pydyn, K Miękus, J Jura, J Kotlinowski - Pharmacological Reports, 2020 - Springer
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide.
Globally, it is currently the most common liver disease and is estimated to affect up to 25% of …