Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
Context There are many published twin studies of schizophrenia. Although these studies
have been reviewed previously, to our knowledge, no review has provided quantitative …
have been reviewed previously, to our knowledge, no review has provided quantitative …
Are we overestimating the genetic contribution to schizophrenia?
EF Torrey - Schizophrenia bulletin, 1992 - academic.oup.com
That genetic factors contribute to the etiology of schizophrenia is no longer debated; the
nature and magnitude of that contribution, however, are still open for discussion. In this …
nature and magnitude of that contribution, however, are still open for discussion. In this …
Schizophrenia as a pseudogenetic disease: A call for more gene-environmental studies
EF Torrey, RH Yolken - Psychiatry research, 2019 - Elsevier
In recent years schizophrenia has been assumed to be largely a genetic disease with
heritability estimates, derived primarily from family and twin studies, of 80%–85%. However …
heritability estimates, derived primarily from family and twin studies, of 80%–85%. However …
The genetics of schizophrenia: current knowledge and future directions
MT Tsuang, MW Gilbertson, SV Faraone - Schizophrenia research, 1991 - Elsevier
Multiple research paradigms have provided evidence for a substantial genetic component in
the etiology of schizophrenic disorders. This article reviews the major research strategies …
the etiology of schizophrenic disorders. This article reviews the major research strategies …
Genetic and environmental influences on schizotypy: a community-based twin study
AW MacDonald III, MF Pogue-Geile… - Schizophrenia …, 2001 - academic.oup.com
This study investigated the factor structure and etiology of four self-report schizotypy
questionnaires during young adulthood (age 18–27) in 98 monozygotic and 59 same-sex …
questionnaires during young adulthood (age 18–27) in 98 monozygotic and 59 same-sex …
Twin studies of schizophrenia: from bow‐and‐arrow concordances to star wars Mx and functional genomics
AG Cardno, II Gottesman - American journal of medical …, 2000 - Wiley Online Library
Twin studies have been vital for establishing an important genetic contribution to the etiology
of schizophrenia. The five newest studies since 1995 from Europe and Japan have …
of schizophrenia. The five newest studies since 1995 from Europe and Japan have …
Heritability of schizophrenia and schizophrenia spectrum based on the nationwide Danish twin register
R Hilker, D Helenius, B Fagerlund, A Skytthe… - Biological …, 2018 - Elsevier
Background Twin studies have provided evidence that both genetic and environmental
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …
The genetics of schizophrenia: a current, genetic-epidemiologic perspective
KS Kendler, SR Diehl - Schizophrenia bulletin, 1993 - academic.oup.com
Abstract In the “Special Report on Schizophrenia” published in the Schizophrenia Bulletin in
1987, the genetic basis of schizophrenia was reviewed. Here, we provide our perspective on …
1987, the genetic basis of schizophrenia was reviewed. Here, we provide our perspective on …
The genetic epidemiology of schizophrenia in a Finnish twin cohort: a population-based modeling study
Background The magnitude of heritability of schizophrenia remains controversial, due in part
to limitations of estimates derived from index twin pairs exclusively. We applied structural …
to limitations of estimates derived from index twin pairs exclusively. We applied structural …
A multivariate perspective on schizotypy and familial association with schizophrenia: a review
SI Tarbox, MF Pogue-Geile - Clinical psychology review, 2011 - Elsevier
Although generally accepted that schizotypal personality disorder diagnosis is more
prevalent among relatives of individuals with schizophrenia and may be associated with …
prevalent among relatives of individuals with schizophrenia and may be associated with …