Deciphering the intracellular dual targeting of the melon necrotic spot virus coat protein, its interaction with host factors and their roles in plant defense

M Sáiz Bonilla - 2023 - riunet.upv.es
[EN] Plant viruses are the causal agents of many plant diseases and the subsequent
economic losses, estimated to be US $60 billion worldwide each year. The melon necrotic …

Dissecting the multifunctional role of the N‐terminal domain of the Melon necrotic spot virus coat protein in RNA packaging, viral movement and interference with …

M Serra‐Soriano, J Antonio Navarro… - Molecular plant …, 2017 - Wiley Online Library
The coat protein (CP) of Melon necrotic spot virus (MNSV) is structurally composed of three
major domains. The middle S‐domain builds a robust protein shell around the viral genome …

The mitochondrial and chloroplast dual targeting of a multifunctional plant viral protein modulates chloroplast‐to‐nucleus communication, RNA silencing suppressor …

JA Navarro, M Saiz‐Bonilla… - The Plant …, 2021 - Wiley Online Library
Plant defense against melon necrotic spot virus (MNSV) is triggered by the viral auxiliary
replicase p29 that is targeted to mitochondrial membranes causing morphological …

Functional analysis of the five melon necrotic spot virus genome-encoded proteins

A Genovés, JA Navarro… - Journal of general …, 2006 - microbiologyresearch.org
Function of the melon necrotic spot virus (MNSV) genome-encoded proteins (p29, p89, p7A,
p7B and p42) has been studied. Protein-expression mutants of an infectious, full-length …

[HTML][HTML] Induction of necrosis via mitochondrial targeting of Melon necrotic spot virus replication protein p29 by its second transmembrane domain

T Mochizuki, K Hirai, A Kanda, J Ohnishi, T Ohki… - Virology, 2009 - Elsevier
The virulence factor of Melon necrotic spot virus (MNSV), a virus that induces systemic
necrotic spot disease on melon plants, was investigated. When the replication protein p29 …

The Intra- and Intercellular Movement of Melon necrotic spot virus (MNSV) Depends on an Active Secretory Pathway

A Genovés, JA Navarro… - Molecular plant-microbe …, 2010 - Am Phytopath Society
Plant viruses hijack endogenous host transport machinery to aid their intracellular spread.
Here, we study the localization of the p7B, the membrane-associated viral movement protein …

Nicotiana benthamiana resistance to non‐adapted Melon necrotic spot virus results from an incompatible interaction between virus RNA and translation initiation …

C Nieto, L Rodríguez‐Moreno… - The Plant …, 2011 - Wiley Online Library
Nicotiana benthamiana has been described as non‐host for Melon necrotic spot virus
(MNSV). We investigated the basis of this resistance using the unique opportunity provided …

Molecular Characterization of a Melon necrotic spot virus Strain That Overcomes the Resistance in Melon and Nonhost Plants

JA Díaz, C Nieto, E Moriones… - Molecular plant …, 2004 - Am Phytopath Society
Resistance of melon (Cucumis melo L.) to Melon necrotic spot virus (MNSV) is inherited as a
single recessive gene, denoted nsv. No MNSV isolates described to date (eg, MNSV-Mα5) …

The Importance of the KR-Rich Region of the Coat Protein of Ourmia melon virus for Host Specificity, Tissue Tropism, and Interference With Antiviral Defense

M Rossi, M Vallino, S Abbà, M Ciuffo… - Molecular Plant …, 2015 - Am Phytopath Society
The N-terminal region of the Ourmia melon virus (OuMV) coat protein (CP) contains a short
lysine/arginine-rich (KR) region. By alanine scanning mutagenesis, we showed that the KR …

[HTML][HTML] A Dual Interaction between the 5′-and 3′-ends of the melon necrotic spot virus (MNSV) RNA genome is required for efficient cap-independent translation

M Miras, AM Rodríguez-Hernández… - Frontiers in Plant …, 2018 - frontiersin.org
In eukaryotes, the formation of a 5′-cap and 3′-poly (A) dependent protein–protein bridge
is required for translation of its mRNAs. In contrast, several plant virus RNA genomes lack …