Drug resistance and the severe side effects of chemotherapy necessitate the development of
novel anticancer drugs. Natural products are a valuable source for drug development …

Chronic diseases are considered a major public health concern worldwide, and most of
these diseases like cancer, cardiovascular, metabolic, and neurological disorders occur due …

Scopoletin is a coumarin synthesized by diverse medicinal and edible plants, which plays a
vital role as a therapeutic and chemopreventive agent in the treatment of a variety of …

Aims Scopoletin is a natural anticarcinogenic and antiviral coumarin component. Many
studies have proved its anti-cancer effect, and after the preliminary screening of this study …

Cancer is considered a leading cause of death worldwide due to its high morbidity and
mortality rate. Conventional treatments for cancer therapy, such as chemotherapy, and …

BACKGROUND Pancreatic cancer is a highly malignant tumor of the gastrointestinal system
whose emerging resistance to chemotherapy has necessitated the development of novel …

Angiogenesis and vasculogenic mimicry (VM) are crucial for the growth and metastasis of
non-small-cell lung cancer (NSCLC). Most tumor angiogenesis inhibitors mainly target …

Angiogenesis plays an important role in many diseases, such as cancer, rheumatoid
arthritis, and diabetic retinopathy. Specific inhibitors of angiogenesis are therefore expected …

A main problem in oncology is the development of drug-resistance. Some plant-derived
lignans are established in cancer therapy, eg. the semisynthetic epipodophyllotoxins …

Ethnopharmacological relevance Smilax china L. is a well-known traditional medicinal plant.
In China, it is a common anti-cancer drug that has been inherited for thousands of years …