Novel receptor specificity of avian gammacoronaviruses that cause enteritis

IN Ambepitiya Wickramasinghe, RP de Vries… - Journal of …, 2015 - Am Soc Microbiol
Viruses exploit molecules on the target membrane as receptors for attachment and entry into
host cells. Thus, receptor expression patterns can define viral tissue tropism and might to …

Identification and Comparison of the Sialic Acid-Binding Domain Characteristics of Avian Coronavirus Infectious Bronchitis Virus Spike Protein

R You, K Liu, M Huang, L Tang, X Zhang… - Journal of …, 2023 - Am Soc Microbiol
Infectious bronchitis virus (IBV) infections are initiated by the transmembrane spike (S)
glycoprotein, which binds to host factors and fuses the viral and cell membranes. The N …

[HTML][HTML] Novel avian coronavirus and fulminating disease in guinea fowl, France

E Liais, G Croville, J Mariette, M Delverdier… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
For decades, French guinea fowl have been affected by fulminating enteritis of unclear
origin. By using metagenomics, we identified a novel avian gammacoronavirus associated …

[HTML][HTML] Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding

LM Parsons, KM Bouwman, H Azurmendi… - Journal of Biological …, 2019 - ASBMB
Avian coronaviruses, including infectious bronchitis virus (IBV), are important respiratory
pathogens of poultry. The heavily glycosylated IBV spike protein is responsible for binding to …

Guinea fowl coronavirus diversity has phenotypic consequences for glycan and tissue binding

KM Bouwman, M Delpont, F Broszeit, R Berger… - Journal of …, 2019 - Am Soc Microbiol
Guinea fowl coronavirus (GfCoV) causes fulminating enteritis that can result in a daily death
rate of 20% in guinea fowl flocks. Here, we studied GfCoV diversity and evaluated its …

Binding of avian coronavirus spike proteins to host factors reflects virus tropism and pathogenicity

INA Wickramasinghe, RP De Vries, A Gröne… - Journal of …, 2011 - Am Soc Microbiol
The binding of viruses to host cells is the first step in determining tropism and pathogenicity.
While avian infectious bronchitis coronavirus (IBV) infection and avian influenza A virus …

N-glycosylation of infectious bronchitis virus M41 spike determines receptor specificity

KM Bouwman, N Habraeken… - Journal of General …, 2020 - microbiologyresearch.org
Infection of chicken coronavirus infectious bronchitis virus (IBV) is initiated by binding of the
viral heavily N-glycosylated attachment protein spike to the alpha-2, 3-linked sialic acid …

Three amino acid changes in avian coronavirus spike protein allow binding to kidney tissue

KM Bouwman, LM Parsons, AJ Berends… - Journal of …, 2020 - Am Soc Microbiol
Infectious bronchitis virus (IBV) infects ciliated epithelial cells in the chicken respiratory tract.
While some IBV strains replicate locally, others can disseminate to various organs, including …

Molecular evolution and emergence of avian gammacoronaviruses

MW Jackwood, D Hall, A Handel - Infection, Genetics and Evolution, 2012 - Elsevier
Coronaviruses, which are single stranded, positive sense RNA viruses, are responsible for a
wide variety of existing and emerging diseases in humans and other animals. The …

The avian coronavirus spike protein

INA Wickramasinghe, SJ Van Beurden, E Weerts… - Virus research, 2014 - Elsevier
Avian coronaviruses of the genus Gammacoronavirus are represented by infectious
bronchitis virus (IBV), the coronavirus of chicken. IBV causes a highly contagious disease …