Background & Aims Subtle inter-patient genetic variation and environmental factors combine
to determine disease progression in non-alcoholic fatty liver disease (NAFLD). Carriage of …

Background & Aims PNPLA3 rs738409 has been associated with an increased risk of liver‐
related events in patients with non‐alcoholic fatty liver disease (NAFLD). In this study, we …

Background An isoleucine> methionine mutation at position 148 in the PNPLA3 gene (p.
I148M, rs738409) has recently been identified as a susceptibility factor for liver damage in …

Aim Some patients with non‐alcoholic fatty liver disease (NAFLD) develop hepatocellular
carcinoma (HCC). Patatin‐like phospholipase domain containing 3 (PNPLA3) rs738409 …

The incidence of hepatocellular carcinoma (HCC) is increasing in Western countries.
Although several clinical factors have been identified, many individuals never develop HCC …

Nonalcoholic fatty liver disease (NAFLD) is an emerging epidemic with high prevalence in
Western countries. Genome‐wide association studies had reported that a variation in the …

OBJECTIVES: The PNPLA3 rs738409 single-nucleotide polymorphism is known to promote
nonalcoholic steatohepatitis (NASH), but its association with fibrosis severity and …

Background and aim: The PNPLA3 rs738409 C> G polymorphism has been found to be
strongly associated with non‐alcoholic fatty liver disease and with alcoholic liver disease …

BACKGROUND: Obesity is a risk factor for cancer, including hepatocellular carcinoma.
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) genetic …

Background & Aims Patients with nonalcoholic fatty liver disease (NAFLD) have an
increased risk for liver-related complications, such as decompensation, hepatocellular …