Depression and anxiety often affect women in relation to reproductive events like menarche,
premenstrual periods, post-partum and perimenopause. A prominent example of the …

Neuroactive steroids are a large group of substances having effect in the brain and on brain
function. The steroids most studied are allopregnanolone (ALLO) …

A growing literature suggests that hormonal fluctuations occurring across the menstrual
cycle, during and after pregnancy, and during the menopausal transition are associated with …

It is estimated that between 70% and 90% of women in their reproductive years experience
some level of discomfort and experience affective and/or somatic symptoms during the …

This article will review neuroactive steroid effects on serotonin and GABA systems, along
with the subsequent effects on cognitive functions. Neurosteroids (such as estrogen …

Neuroactive steroids are potent endogenous neuromodulators with rapid actions in the
central nervous system. Neuroactive steroids have been claimed to have specific …

Neuroactive steroids modulate neurotransmission through modulation of specific
neurotransmitter receptors such as γ-aminobutyric acid type A (GABAA) receptors …

Publisher Summary This chapter focuses on the role of sex hormones, particularly
estrogens, androgens and progestins, as mediators of mood and affect. The limbic system, a …

The term “neurosteroid”(NS) was introduced by Baulieu in 1981 to name a steroid hormone,
dehydroepiandrosterone sulfate (DHEAS), that was found at high levels in the brain long …

Some women have negative mood symptoms, caused by progestagens in hormonal
contraceptives or sequential hormone therapy or by progesterone in the luteal phase of the …