Quinoline derivatives are important natural products and pharmaceuticals, but their
synthesis can be challenging due to poor yields, harsh reaction conditions, and instability of …

Tertiary alcohols are widely represented in nature and among bioactive molecules. Their
importance is attested by the continuous efforts to meet the challenge of their stereoselective …

A novel and efficient biocatalyzed methodology for the construction of functionalized
quinazolinone derivatives via tandem/hydrolysis/decarboxylation/cyclization and …

Abstract The 1-aryl-tetrahydroisoquinoline (1-aryl-THIQ) moiety is found in many biologically
active molecules. Single enantiomer chemical syntheses are challenging and although …

Type I aldolases catalyze carbon–carbon bond-forming reactions to form a diverse set of
products in nature but often display high selectivity for their natural substrates. One such …

Concise synthesis of functionalized quinolines has received continuous research attention
owing to the biological importance and synthetic potential of bicyclic N-heterocycles …

Quinolines are important building blocks for the synthesis of natural products and
pharmaceuticals. In comparison with classical methods, dehydroaromatization of 1, 2, 3, 4 …

One-pot reactions that combine non-enzymatic and biocatalytic transformations represent an
emerging strategy in chemical synthesis. Some of the most powerful chemoenzymatic …

Nature has developed complexity-generating reactions within natural product biosynthetic
pathways. However, direct utilization of these pathways to prepare compound libraries …

We report the regioselective synthesis of furo-and thienoquinolines by using an amine
oxidase-inspired catalyst (1, 10-phenanthroline-5, 6-dione) and an abundant Lewis acid …