Severe forms of pulmonary arterial hypertension (PAH) are characterized by various
degrees of remodeling of the pulmonary arterial vessels, which increases the pulmonary …

At present, six groups of chronic pulmonary hypertension (PH) are described. Among these,
group 1 (and 1′) comprises a group of diverse diseases termed pulmonary arterial …

Abstract World Health Organization category 1 pulmonary hypertension (PH) is a
heterogeneous syndrome in which PH originates in the small pulmonary arteries and is …

Pulmonary arterial hypertension (PAH) is responsible for the premature death mainly
because of progressive and severe heart failure. This disease is characterized by increased …

Pulmonary arterial hypertension (PAH) is a progressive pulmonary vasoproliferative
disorder characterized by the development of unique neointimal lesions, including …

Despite improved understanding of the pathobiology of pulmonary arterial hypertension
(PAH), it remains a severe and progressive disease, usually culminating in right heart …

Pulmonary arterial hypertension (PAH) is defined foremost by a distinct pulmonary vascular
pathophenotype that occurs as a result of dysregulated vascular cell proliferation, intimal …

Pulmonary arterial hypertension (PAH) is a disease characterized by progressive loss and
remodeling of the pulmonary arteries, resulting in right heart failure and death. Until recently …

Rationale: The complex pathologies associated with severe pulmonary arterial hypertension
(PAH) in humans have been a challenge to reproduce in mice due to the subtle phenotype …

Pulmonary arterial hypertension (PAH) is a progressive and lethal pulmonary vascular
disease (PVD). Although in recent years outcome has improved by new treatments that …