PHBV/PCL microparticles for controlled release of resveratrol: physicochemical characterization, antioxidant potential, and effect on hemolysis of human erythrocytes

JBE Mendes, MK Riekes, VM de Oliveira… - The Scientific World …, 2012 - Wiley Online Library
Microparticles of poly (3‐hydroxybutyrate‐co‐3‐hydroxyvalerate)(PHBV) and poly (ε‐
caprolactone)(PCL) containing resveratrol were successfully prepared by simple …

Microparticles prepared with poly(hydroxybutyrate-co-hydroxyvalerate) and poly(ε-caprolactone) blends to control the release of a drug model

MIZ Lionzo, MI Ré, SS Guterres… - Journal of …, 2007 - Taylor & Francis
The objective of this work was to verify the influence of the poly (ϵ-caprolactone) PCL
concentration in poly (hydroxybutyrate-co-hydroxyvalerate) P (HBHV)/PCL microparticles …

Evaluation of oral carvedilol microparticles prepared by simple emulsion technique using poly (3-hydroxybutyrate-co-3-hydroxyvalerate) and polycaprolactone as …

MK Riekes, FM Barboza, D Dalla Vecchia… - Materials Science and …, 2011 - Elsevier
Polymeric microparticles containing carvedilol (CRV) were obtained successfully using a
simple emulsion/organic evaporating method. Three different formulations were developed …

Preparation and characterization of biodegradable polyhydroxybutyrate-co-hydroxyvalerate/polyethylene glycol-based microspheres

A Monnier, C Rombouts, D Kouider, I About… - International Journal of …, 2016 - Elsevier
The in vivo effectiveness of biomolecules may be limited by their rapid diffusion in the body
and short half-life time. Encapsulation of these biomolecules allows protecting them against …

Influence of the Polymer and Solvent Variables on the Nanoencapsulation of the Flavonoid Quercetin: Preliminary Study Based on Eudragit® Polymers

JH Elizondo-Luevano, R Castro-Ríos… - Applied Sciences, 2023 - mdpi.com
Featured Application A methodology was developed for the efficient nanoencapsulation of
non-water-soluble biomolecules, such as the flavonoid quercetin, through the …

Development of microparticles for controlled release of resveratrol to adipose tissue and the impact of drug loading on particle morphology and drug release

C Isely, MA Hendley, KP Murphy, S Kader… - International journal of …, 2019 - Elsevier
Resveratrol is a small molecule produced by various plants with a remarkable range of
beneficial functions in animals. One of these is stimulating signaling pathways in adipose …

Synthesis and characterization of polyhydroxybutyrate-co-hydroxyvalerate nanoparticles for encapsulation of quercetin

S Lightfoot Vidal, C Rojas… - Journal of Bioactive …, 2016 - journals.sagepub.com
Polyhydroxybutyrate-co-hydroxyvalerate has been identified as a useful polymer for
biomedical application due to its biocompatibility and processability. Polyhydroxybutyrate-co …

Resveratrol cross-linked chitosan loaded with phospholipid for controlled release and antioxidant activity

H Jeong, KJ Samdani, DH Yoo, DW Lee… - International journal of …, 2016 - Elsevier
Despite the therapeutic effects of resveratrol, its clinical application is restricted by its poor
oral bioavailability and low water solubility. To overcome these physicochemical and …

Injectable methotrexate loaded polycaprolactone microspheres: physicochemical characterization, biocompatibility, and hemocompatibility evaluation

M Dhanka, C Shetty, R Srivastava - Materials Science and Engineering: C, 2017 - Elsevier
In this study, bare polycaprolactone microspheres (PCL MPs) and methotrexate (MTX)
loaded PCL microspheres (MTX-PCL MPs) have been developed by oil-in-water emulsion …

PCL/PHBV microparticles as innovative carriers for oral controlled release of manidipine dihydrochloride

FM Barboza, WM Machado… - The Scientific World …, 2014 - Wiley Online Library
Microparticles of poly (ε‐caprolactone)(PCL) and poly (3‐hydroxybutyrate‐co‐3‐
hydroxyvalerate)(PHBV) containing manidipine dihydrochloride (MAN) were successfully …