[HTML][HTML] M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis
J Hou, J Shi, L Chen, Z Lv, X Chen, H Cao… - Cell Communication and …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by
the histopathological pattern of usual interstitial pneumonia and is associated with a high …
the histopathological pattern of usual interstitial pneumonia and is associated with a high …
TNF‐α‐induced NF‐κB activation promotes myofibroblast differentiation of LR‐MSCs and exacerbates bleomycin‐induced pulmonary fibrosis
J Hou, T Ma, H Cao, Y Chen, C Wang… - Journal of cellular …, 2018 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease of
unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR …
unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR …
[HTML][HTML] Inhibition of Wnt/β-catenin signaling suppresses myofibroblast differentiation of lung resident mesenchymal stem cells and pulmonary fibrosis
H Cao, C Wang, X Chen, J Hou, Z Xiang, Y Shen… - Scientific reports, 2018 - nature.com
An emerging paradigm proposes a crucial role for lung resident mesenchymal stem cells
(LR-MSCs) via a fibroblastic transdifferentiation event in the pathogenesis of idiopathic …
(LR-MSCs) via a fibroblastic transdifferentiation event in the pathogenesis of idiopathic …
Macrophage-secreted TSLP and MMP9 promote bleomycin-induced pulmonary fibrosis
G Li, F Jin, J Du, Q He, B Yang, P Luo - Toxicology and applied …, 2019 - Elsevier
Idiopathic pulmonary fibrosis is a pathological result of dysfunctional repair response to
tissue injury, leading to chronically impaired gas exchange and death. Macrophages are …
tissue injury, leading to chronically impaired gas exchange and death. Macrophages are …
[HTML][HTML] The hedgehog and Wnt/β-catenin system machinery mediate myofibroblast differentiation of LR-MSCs in pulmonary fibrogenesis
X Chen, C Shi, H Cao, L Chen, J Hou, Z Xiang… - Cell death & …, 2018 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal lung disease that is
characterized by enhanced changes in stem cell differentiation and fibroblast proliferation …
characterized by enhanced changes in stem cell differentiation and fibroblast proliferation …
IL-8 mediates idiopathic pulmonary fibrosis mesenchymal progenitor cell fibrogenicity
L Yang, J Herrera, A Gilbertsen, H Xia… - … of Physiology-Lung …, 2018 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, but the
mechanisms driving progression remain incompletely defined. We previously reported that …
mechanisms driving progression remain incompletely defined. We previously reported that …
[HTML][HTML] Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2
AP Epa, TH Thatcher, SJ Pollock, LA Wahl, E Lyda… - PloS one, 2015 - journals.plos.org
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with very
few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which …
few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which …
[HTML][HTML] Mesenchymal stem cells in idiopathic pulmonary fibrosis
X Li, S Yue, Z Luo - Oncotarget, 2017 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a major cause of respiratory failure in critically ill
patients and common outcome of various lung interstitial diseases. Its mortality remains …
patients and common outcome of various lung interstitial diseases. Its mortality remains …
Mesenchymal stromal cells in animal bleomycin pulmonary fibrosis models: a systematic review
Idiopathic pulmonary fibrosis is an inexorably progressive lung disease with few available
treatments. New therapeutic options are needed. Stem cells have generated much …
treatments. New therapeutic options are needed. Stem cells have generated much …
The Shh/Gli signaling cascade regulates myofibroblastic activation of lung-resident mesenchymal stem cells via the modulation of Wnt10a expression during …
H Cao, X Chen, J Hou, C Wang, Z Xiang… - Laboratory …, 2020 - nature.com
Lung-resident mesenchymal stem cells (LR-MSCs) are important regulators of lung repair
and regeneration, and evidence suggests that this cell population also plays a vital role in …
and regeneration, and evidence suggests that this cell population also plays a vital role in …
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