BACKGROUND AND AIMS: The role of free radicals has long been proposed as a cause for
the aging process. Oxidative stress is considered a major factor for altering many …

Paraoxonase 1 (PON1) is an HDL bound enzyme which plays a key role in the protection of
LDL and HDL from oxidation by hydrolyzing activated phospholipids and lipid peroxide …

Objective There is much evidence linking the involvement of oxidative stress in the
pathogenesis of aging. Paraoxonase 1 (PON1) is an HDL-associated antioxidant enzyme …

The incidence of atherosclerosis increases with age. Oxidative changes in proteins and
lipids are considered to be among the molecular mechanisms leading to endothelial …

Paraoxonase (PON1) is principally complexed to HDL and is responsible, at least in part, for
its antioxidant properties. PON1 activity decreases in several pathologies associated with …

Aging is defined as the accumulation of progressive organ dysfunction. There is much
evidence linking the involvement of oxidative stress in the pathogenesis of aging. With …

Summary Paraoxonase 1 (PON1) seems to have a relevant role in detoxifying processes
and in atherosclerosis. The aim of this study was to determine PON1 activity, the total …

Background Paraoxonase 1 (PON1) is an enzyme associated with High density lipoprotein
(HDL) in blood and it is considered to have antioxidant and antiatherogenic properties …

Low-density lipoproteins (LDLs), when modified by free radicals derived from artery wall
cells, induce atherosclerosis. In contrast to oxidized LDL (ox-LDL), high-density lipoproteins …

Human Paraoxonase (PON1) is a High-Density Lipoprotein (HDL)-associated esterase that
hydrolyses lipo-peroxides. PON1 has recently attracted attention as a protective factor …