[HTML][HTML] The complex interplay between depression and multimorbidity in late life: risks and pathways

F Triolo, L Harber-Aschan, MB Murri… - Mechanisms of Ageing …, 2020 - Elsevier
Multimorbidity and depression are complex multifactorial conditions with major implications
for older individuals, their families, and healthcare providers. In this scoping review, we …

Late-life depression and multimorbidity trajectories: the role of symptom complexity and severity

F Triolo, L Sjöberg, A Calderón-Larrañaga… - Age and …, 2023 - academic.oup.com
Introduction as late-life depression is associated with poor somatic health, we aimed to
investigate the role of depression severity and symptom phenotypes in the progression of …

[HTML][HTML] Biological factors influencing depression in later life: role of aging processes and treatment implications

SM Szymkowicz, AR Gerlach, D Homiack… - Translational …, 2023 - nature.com
Late-life depression occurring in older adults is common, recurrent, and malignant. It is
characterized by affective symptoms, but also cognitive decline, medical comorbidity, and …

A practical approach to assess depression risk and to guide risk reduction strategies in later life

OP Almeida, H Alfonso, J Pirkis, N Kerse… - International …, 2011 - cambridge.org
Background: Many factors have been associated with the onset and maintenance of
depressive symptoms in later life, although this knowledge is yet to be translated into …

Current understanding of the neurobiology and longitudinal course of geriatric depression

SL Weisenbach, A Kumar - Current psychiatry reports, 2014 - Springer
Late life depression is a complex disease associated with a number of contributing
neurobiological factors, including cerebrovascular disease, neurodegeneration, and …

[HTML][HTML] Multimorbidity and depression among older adults in India: Mediating role of functional and behavioural health

S Ansari, A Anand, B Hossain - PLoS One, 2022 - journals.plos.org
Researchers have long been concerned about the association between depression and the
prevalence of multiple chronic diseases or multimorbidity in older persons. However, the …

Risk factors for multimorbidity in adulthood: A systematic review

C Tazzeo, A Zucchelli, DL Vetrano, J Demurtas… - Ageing Research …, 2023 - Elsevier
Background Multimorbidity, the coexistence of multiple chronic diseases in an individual, is
highly prevalent and challenging for healthcare systems. However, its risk factors remain …

Comorbidity of late life depression: an opportunity for research on mechanisms and treatment

GS Alexopoulos, K Buckwalter, J Olin, R Martinez… - Biological …, 2002 - Elsevier
Late life depression principally affects individuals with other medical and psychosocial
problems, including cognitive dysfunction, disability, medical illnesses, and social isolation …

Multimorbidity in older adults

ME Salive - Epidemiologic reviews, 2013 - academic.oup.com
Multimorbidity, the coexistence of 2 or more chronic conditions, has become prevalent
among older adults as mortality rates have declined and the population has aged. We …

The impact of psychosocial factors on late-life depression

PA Areán, CF Reynolds III - Biological Psychiatry, 2005 - Elsevier
Mental illnesses in later life are multidimensional phenomena that occur in interpersonal,
psychosocial, and biological contexts. With depression used as an example, the purpose of …