Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review

Y Mostmans, K De Smedt, B Richert, D Elieh Ali Komi… - Allergy, 2021 - Wiley Online Library
Chronic urticaria (CU) is a chronic inflammatory mast cell‐driven disorder. Endothelial cells
(ECs) contribute importantly to key features of CU. Several markers of EC (dys) function in …

Mediators of inflammation and angiogenesis in chronic spontaneous urticaria: are they potential biomarkers of the disease?

I Puxeddu, F Pratesi, D Ribatti… - Mediators of …, 2017 - Wiley Online Library
In chronic spontaneous urticaria (CSU), different pathophysiological mechanisms,
potentially responsible for the development of the disease, have been recently described. It …

Advanced biomarkers: therapeutic and diagnostic targets in urticaria

Y Zhang, H Zhang, S Du, S Yan, J Zeng - International archives of …, 2021 - karger.com
Urticaria is a type of skin disease characterized by rapid onset of hives (superficial dermis
edema, erythema, pruritus, or burning sensation). According to whether the natural course …

A comprehensive approach to urticaria: from clinical presentation to modern biological treatments through pathogenesis

M Folci, G Ramponi, E Brunetta - … Medicine, Volume 12: Stem Cells in …, 2021 - Springer
Urticaria is characterized by the cutaneous presence of wheals (hives), angioedema or both.
Acute and chronic urticaria are distinguished based on a duration of less or more than 6 …

Acute‐phase response in chronic urticaria

A Kasperska‐Zajac - Journal of the European Academy of …, 2012 - Wiley Online Library
The patterns of acute‐phase response (APR) biomarkers differ upon various inflammatory
conditions. Little information is available on the systemic inflammatory response in …

Chronic spontaneous urticaria and the extrinsic coagulation system

Y Yanase, S Takahagi, M Hide - Allergology International, 2018 - jstage.jst.go.jp
abstract Chronic spontaneous urticaria (CSU) is a common skin disorder characterized by
daily or almost daily recurring skin edema and flare with itch. Recently, the activation of the …

Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria

R Grzanka, A Damasiewicz-Bodzek… - Allergy, Asthma & …, 2018 - Springer
Background Chronic spontaneous urticaria (CSU) is associated with activation of systemic
inflammatory response and coagulation/fibrinolysis. Aim To study whether there is a …

In chronic spontaneous urticaria, high numbers of dermal endothelial cells, but not mast cells, are linked to recurrent angio‐oedema

D Terhorst, I Koti, K Krause, M Metz… - Clinical and …, 2018 - academic.oup.com
Background Chronic spontaneous urticaria (CSU) is an inflammatory skin disorder
characterized by recurrent weals, angio‐oedema or both. Recent studies have shown that …

Urticaria and angioedema: understanding complex pathomechanisms to facilitate patient communication, disease management, and future treatment

GN Konstantinou, MA Riedl, P Valent, I Podder… - The Journal of Allergy …, 2023 - Elsevier
Chronic spontaneous urticaria (CSU) is primarily a T2-dominant disease with a complex
genetic background. Skin mast cell activation can be induced not only via the IgE-FcεRI axis …

Potential blood biomarkers in chronic spontaneous urticaria

P Kolkhir, F André, MK Church… - Clinical & …, 2017 - Wiley Online Library
Chronic spontaneous urticaria (CSU) is a mast cell‐driven disease that is defined as the
recurrence of weals, angioedema or both for> 6 weeks due to known or unknown causes. As …