The longitudinal associations of inflammatory biomarkers and depression revisited: systematic review, meta-analysis, and meta-regression
The innate immune system is dysregulated in depression; however, less is known about the
longitudinal associations of depression and inflammatory biomarkers. We investigated the …
longitudinal associations of depression and inflammatory biomarkers. We investigated the …
CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies
V Valkanova, KP Ebmeier, CL Allan - Journal of affective disorders, 2013 - Elsevier
Background Inflammatory markers are raised in cross-sectional studies of depressed
patients and may represent an important mediating factor for behaviour, neural plasticity and …
patients and may represent an important mediating factor for behaviour, neural plasticity and …
Longitudinal association between depression and inflammatory markers: results from the Netherlands study of depression and anxiety
F Lamers, Y Milaneschi, JH Smit, RA Schoevers… - Biological …, 2019 - Elsevier
Background While cross-sectional associations of inflammatory markers interleukin-6 (IL-6)
and C-reactive protein with major depressive disorder are well established, evidence for …
and C-reactive protein with major depressive disorder are well established, evidence for …
Longitudinal association of inflammation with depressive symptoms: a 7-year cross-lagged twin difference study
Background The direction of the association between inflammation and depressive
symptoms remains inconsistent. The objective of this study was to evaluate the temporal …
symptoms remains inconsistent. The objective of this study was to evaluate the temporal …
Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis
Objective: To assess the magnitude and direction of associations of depression with C-
reactive protein (CRP), interleukin (IL)-1, and IL-6 in community and clinical samples …
reactive protein (CRP), interleukin (IL)-1, and IL-6 in community and clinical samples …
Association between systemic inflammation and individual symptoms of depression: a pooled analysis of 15 population-based cohort studies
Objective: Evidence from anti-inflammatory drug trials for the treatment of depression has
been inconsistent. This may be ascribed to the differing symptom-specific effects of …
been inconsistent. This may be ascribed to the differing symptom-specific effects of …
[HTML][HTML] Inflammatory markers in depression: a meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls
EF Osimo, T Pillinger, IM Rodriguez… - Brain, behavior, and …, 2020 - Elsevier
Importance The magnitude and variability of cytokine alterations in depression are not clear.
Objective To perform an up to date meta-analysis of mean differences of immune markers in …
Objective To perform an up to date meta-analysis of mean differences of immune markers in …
Association of systemic inflammatory biomarkers with depression risk: results from national health and nutrition examination survey 2005–2018 analyses
X Li, J Huan, L Lin, Y Hu - Frontiers in psychiatry, 2023 - frontiersin.org
Background/Aim Depression has become a multiple disease worldwide, and is closely
related to the systemic inflammatory response. Methods Based on the data of the National …
related to the systemic inflammatory response. Methods Based on the data of the National …
Low-grade inflammation predicts persistence of depressive symptoms
A Zalli, O Jovanova, WJG Hoogendijk, H Tiemeier… - …, 2016 - Springer
Rationale Evidence suggests that depression is cross-sectionally and longitudinally
associated with activation of inflammatory response system. A few studies, however, have …
associated with activation of inflammatory response system. A few studies, however, have …
[HTML][HTML] Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder
R Haapakoski, J Mathieu, KP Ebmeier… - Brain, behavior, and …, 2015 - Elsevier
Cumulative meta-analyses are used to evaluate the extent to which further studies are
needed to confirm or refute a hypothesis. We used this approach to assess observational …
needed to confirm or refute a hypothesis. We used this approach to assess observational …
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