Periodontal ligament stem cells (PDLCs) can be used as a valuable source in cell therapies
to regenerate bone tissue. However, the potential therapeutic outcomes are unpredictable …

Background Mesenchymal cells' biology has been an important investigative tool to
maximize bone regeneration through tissue engineering. Here we used mesenchymal cells …

Periodontitis is an inflammatory disease characterized by alveolar bone loss. Periodontal
ligament stem cells (PDLSCs) have osteogenic differentiation potential, which can be …

Periodontal defects' localization affects wound healing and bone remodeling, with faster
healing in the upper jaw compared to the lower jaw. While differences in blood supply …

Periodontal ligament cells (PDLCs) have well documented osteogenic potential; however,
this commitment can be highly heterogenous, limiting their applications in tissue …

ABSCTRAT Objective Periodontal regeneration poses challenges due to the periodontium's
complexity, relying on mesenchymal cells from the periodontal ligament (hPDLSCs) to …

Background Cellular plasticity and complex functional requirements of the periodontal
ligament (PDL) assume a local stem cell (SC) niche to maintain tissue homeostasis and …

Background The periodontal ligament cells (PDLCs) contain heterogeneous cell
populations and possess stem-cell-like properties. PDLCs have attracted considerable …

Background Periodontal ligament stem cells (PDLSCs) have been proposed as therapeutic
candidates in periodontal diseases and periodontium defects. Paracrine factors of PDLSCs …

Background Long noncoding RNAs (lncRNAs) are regulatory molecules that participate in
biological processes such as stem cell differentiation. Periodontal ligament stem cells …