Anti-sperm Antibodies as an Increasing Threat to Male Fertility: Immunological Insights, Diagnostic and Therapeutic Strategies

AG Mukherjee, AV Gopalakrishnan - Reproductive Sciences, 2024 - Springer
It is a fact that sperm possess antigenic properties. Substantial scientific research suggests
that specific antibodies that attach to sperm antigens can induce infertility in both humans …

Antisperm immunity and infertility

JC Lu, YF Huang, NQ Lu - Expert review of clinical immunology, 2008 - Taylor & Francis
Immunoinfertility is one of several causes of infertility in humans. Although progress on
antisperm immunity and infertility has advanced during the past three decades, the nature of …

[HTML][HTML] Antisperm antibody testing: a comprehensive review of its role in the management of immunological male infertility and results of a global survey of clinical …

S Gupta, R Sharma, A Agarwal, F Boitrelle… - The world journal of …, 2022 - ncbi.nlm.nih.gov
Antisperm antibodies (ASA), as a cause of male infertility, have been detected in infertile
males as early as 1954. Multiple causes of ASA production have been identified, and they …

[PDF][PDF] A Review: Have we Identified the Risk Factors for the Formation of Antisperm Antibodies? Androl Gynecol: Curr Res 1: 1

V Tennakoon - of, 2013 - researchgate.net
Spermatozoa were first demonstrated as immunogenic more than a century ago.
Subsequent research has lead to the discovery of antisperm antibodies (ASA) and their …

A survey of anti-sperm antibodies in infertile couples

NH HADI, M Ghafourzadeh - 2007 - sid.ir
The presence of ANTI-SPERM ANTIBODIES (ASA) in semen or serum may impair sperm
function leading to immunological infertility. The aim of this study was to investigate the …

Diversity of antisperm antibodies bound to sperm surface in male immunological infertility

H Shibahara, T Tsunoda, A Taneichi… - American Journal of …, 2002 - Wiley Online Library
PROBLEM: The presence of antisperm antibodies (ASA) in males can reduce fecundity,
however, relationship between the two is disputed. This study was performed to investigate if …

Diversity of the inhibitory effects on fertilization by anti‐sperm antibodies bound to the surface of ejaculated human sperm

H Shibahara, Y Shiraishi, Y Hirano, T Suzuki… - Human …, 2003 - academic.oup.com
BACKGROUND: The presence of anti‐sperm antibodies (ASA) in males can reduce
fecundity. However, it has been shown that there is a diversity of ASA bound to the sperm …

Immunology and immunopathology of the male genital tract: antisperm immunity in natural and assisted reproduction

F Lombardo, L Gandini, F Dondero… - Human Reproduction …, 2001 - academic.oup.com
Research conducted in the last 40 years has provided evidence that antisperm antibodies
(ASA) can impair the fertilizing capacity of human spermatozoa. It is established that ASA …

Immunology and immunopathology of the male genital tract: Experimental models to investigate the pathology of antisperm antibodies: approaches and problems

R Clayton, H Moore - Human Reproduction Update, 2001 - academic.oup.com
Antisperm antibodies (ASA) can interfere with sperm function and fertilization. But we still
know relatively little about the specific mechanisms that elicit an auto-immune response and …

Modalities for treatment of antisperm antibody mediated infertility: novel perspectives

RK Naz - American Journal of Reproductive Immunology, 2004 - Wiley Online Library
Immunoinfertility because of antisperm antibodies (ASA) is an important cause of infertility in
humans. The incidence of ASA in infertile couples is 9–36% depending on the reporting …