Genome editing of a rice CDP-DAG synthase confers multipathogen resistance

G Sha, P Sun, X Kong, X Han, Q Sun, L Fouillen… - Nature, 2023 - nature.com
The discovery and application of genome editing introduced a new era of plant breeding by
giving researchers efficient tools for the precise engineering of crop genomes. Here we …

Genome editing technologies for rice improvement: progress, prospects, and safety concerns

K Zafar, KEM Sedeek, GS Rao, MZ Khan… - Frontiers in Genome …, 2020 - frontiersin.org
Rice (Oryza sativa) is an important staple food crop worldwide; to meet the growing
nutritional requirements of the increasing population in the face of climate change …

Synthesis-dependent repair of Cpf1-induced double strand DNA breaks enables targeted gene replacement in rice

S Li, J Li, J Zhang, W Du, J Fu, S Sutar… - Journal of …, 2018 - academic.oup.com
The recently developed CRISPR (clustered regularly interspaced short palindromic
repeats)/Cpf1 system expands the range of genome editing and is emerging as an …

High‐efficiency prime editing enables new strategies for broad‐spectrum resistance to bacterial blight of rice

A Gupta, B Liu, QJ Chen, B Yang - Plant Biotechnology Journal, 2023 - Wiley Online Library
Using genetic resistance against bacterial blight (BB) caused by Xanthomonas oryzae
pathovar oryzae (Xoo) is a major objective in rice breeding programmes. Prime editing (PE) …

A proposed regulatory framework for genome-edited crops

S Huang, D Weigel, RN Beachy, J Li - Nature genetics, 2016 - nature.com
Crop breeding is being revolutionized by rapid progress in DNA sequencing and targeted
alteration of DNA sequences by genome editing. Here we propose a regulatory framework …

Genome-edited powdery mildew resistance in wheat without growth penalties

S Li, D Lin, Y Zhang, M Deng, Y Chen, B Lv, B Li, Y Lei… - Nature, 2022 - nature.com
Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring
disease resistance,. However, S genes are implicated in many essential biological functions …

Genome editing for plant disease resistance: applications and perspectives

K Yin, JL Qiu - … Transactions of the Royal Society B, 2019 - royalsocietypublishing.org
Diseases severely affect crop yield and quality, thereby threatening global food security.
Genetic improvement of plant disease resistance is essential for sustainable agriculture …

High-efficiency TALEN-based gene editing produces disease-resistant rice

T Li, B Liu, MH Spalding, DP Weeks, B Yang - Nature biotechnology, 2012 - nature.com
Figure 1 High-efficiency targeted gene editing using TALENs.(a) Overlapping elements
targeted by two pairs (1 and 2) of designer TALENs in the Os11N3 promoter.(b–d) …

Regulatory uncertainty over genome editing

HD Jones - Nature plants, 2015 - nature.com
Genome editing opens up opportunities for the precise and rapid alteration of crops to boost
yields, protect against pests and diseases and enhance nutrient content. The extent to which …

[PDF][PDF] Precise modifications of both exogenous and endogenous genes in rice by prime editing

H Li, J Li, J Chen, L Yan, L Xia - Molecular Plant, 2020 - cell.com
Harnessing genetic diversity and the introduction of elite alleles from wild relatives or
landraces into commercial cultivars has been a major goal in crop breeding programs …